Exposure to high levels of genotoxic stress, such as high-dose ionizing radiation, increases both cancer and noncancer risks. However, it remains debatable whether low-dose ionizing radiation reduces cellular function, or rather induces hormetic health benefits. Here, we investigated the effects of total-body γ-ray radiation on muscle stem cells, called satellite cells. Adult C57BL/6 mice were ...

background: human is exposed to radiation in their environment with or without their consent and the exposure to natural background radiation is an unpreventable event on earth. materials and methods: an in situ assessment of the indoor and outdoor background radiation in akwanga and keffi towns of nasarawa state nigeria was carried out using a halogen-quenched geiger muller (gm) detector (insp...

ever since studies on uranium miners established the presence of a positive risk coefficient for the occurrence of lung cancer in miners exposed to elevated levels of 222rn and its progeny, there was a great upsurge of interest in the measurement of 222rn in the environment and considerable data is generated on the levels of 222rn in the environment across the worlds and is periodically reporte...

background and objective: professional radiation workers are occupationally exposed to long-term low levels of ionizing radiation. occupational health hazards from radiation exposure, in a large occupational segment of the population, are of special concern. biological dosimetry can be performed in addition to physical dosimetry with the aim of individual dose assessment and biological effects....

Human fibroblast cells obtained from a normal individual and immortalized by introduction of the hTERT gene were irradiated with 0 to 5 Gy of acute high-dose-rate radiation (1.8 Gy/min) or chronic low-dose-rate radiation (0.3 mGy/min) in the G0 phase, and p53 activation was studied. After high-dose-rate irradiation, a dose-dependent induction of Ser15 phosphorylation was observed, whereas after...

background: the trabecular bone changes in the tibia of c3h/hen mice were measured 12 weeks after whole body irradiation with various doses of fast neutrons (0-2.4 gy) or 137cs-generated gamma-rays (0-6 gy). materials and methods: serum calcium, phosphorus, estradiol concentration and alkaline phosphatase activity were measured. tibiae were analyzed using microcomputed tomography. biomechanical...