background there is limited data on the natural history of autoimmune hepatitis (aih) and on the long-term follow-up of aih patients who have been referred for regular medical attention. objectives we evaluated the clinical presentation and natural history of aih in a large cohort of type i aih patients from iran. patients and methods between 1997 and 2008, 102 patients were enrolled in the stu...

detection and modification of the risk factors of stroke may be the most effective strategy for preventing its often irreversible consequences. a longitudinal prospective study was implemented to evaluate the effect of several risk factors on the course of cerebrovascular disease. the study groups were composed of 3s8 normal volunteers, and 308 patients with transient ischemic attacks. the two ...

Edvinsson, D. 2017. Attention Deficit/Hyperactivity Disorder in Adults. Prevalence, Psychiatric Comorbidities and Long-term Outcome. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1353. 67 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-513-0029-0. Attention Deficit/Hyperactivity Disorder (ADHD) was originally thought to occur only in children, bu...

Twenty eight children with herpes simplex encephalitis were followed up for a mean of 5.5 years. Two children died and 26 survived, of whom 16 were left with no neurological sequelae and 10 had persistent neurological sequelae. Mean (SD) Glasgow coma score was significantly lower in the patients with neurological sequelae (7.7 (1.5)) and the patients who died (4.5 (0.7)), compared with the pati...

Kawasaki disease was first reported in 1967 by Japanese pediatrician Tomisaku Kawasaki as an acute febrile syndrome mainly affecting the skin, mucosa, and lymph nodes.1 Although initially recognized as benign, this syndrome was subsequently acknowledged to have a serious complication of coronary artery aneurysm,2 and it has gained the worldwide interest of pediatricians and pediatric cardiologi...

Carotid artery stenting (CAS) is a less invasive technique than carotid endarterectomy (CEA) for prevention of stroke in patients with carotid artery stenosis. Although reports from high-volume centers have demonstrated acceptable short-term results after CAS, randomized controlled trials (RCT) have demonstrated inferior results, in terms of stroke and death in the perioperative phase, after CA...

AIM The long-term outcome of the Dutch pyridoxine-dependent epilepsy cohort and correlations between patient characteristics and follow-up data were retrospectively studied. METHOD Fourteen patients recruited from a national reference laboratory were included (four males, 10 females, from 11 families; median age at assessment 6y; range 2y 6mo-16y). The following data were retrieved: sex; age ...

BACKGROUND Doctors need reliable data on outcome in order to help parents faced with difficult decisions about termination of an affected pregnancy or treatment after birth. AIM To determine survival, health and lifestyle at the mean age of 30 years in a complete cohort of adults born with open spina bifida. DESIGN OF STUDY Prospective cohort study. PARTICIPANTS Well-documented cohort of ...