1.1 ABSTRACT The LogP model characterizes the performance of modern parallel machines with a small set of parameters: the communication latency (L), overhead (o), bandwidth (g), and the number of processors (P). In this paper, we analyze four parallel sorting algorithms (bitonic, column, radix, and sample sort) under LogP. We develop implementations of these algorithms in a parallel extension t...

Our goal is to perform in-vitro biotransformation of Prodrugs of ibuprofen+paracetamol, diclofenac sodium+paracetamol and ibuprofen+diclofenac sodium by acidic and alkaline hydrolysis of both ester (–COO–) and amide (–CONH–) linkages into free drugs and chromatographically separation of their Rt in HPLC. Since both ester (–COO–) and amide (–CONH–) linkages are susceptible to hydrolysis in both ...

This paper presents a framework of using resource metrics to characterize the various models of parallel computation. Our framework reflects the approach of recent models to abstract architectural details into several generic parameters, which we call resource metrics. We examine the different resource metrics chosen by different parallel models, categorizing the models into four classes: the b...

in this paper, the quantitative structure activity-relationship (qsar) of the ccr2b receptor inhibitors was scrutinized. firstly, the molecular descriptors were calculated using the dragon package. then, the stepwise multiple linear regressions (sw-mlr) and the genetic algorithm multiple linear regressions (ga-mlr) variable selection methods were subsequently employed to select and implement th...

This study presents some mathematical methods for estimating the critical properties of 40 different types of alkanes and their derivatives including critical temperature, critical pressure and critical volume. This algorithm used QSPR modeling based on graph theory, several structural indices, and geometric descriptors of chemical compounds. Multiple linear regression was used to estimate the ...

An overview on the development of QSPR/QSAR equations using various descriptor mining techniques and multilinear regression analysis in the framework of program CODESSA (Comprehensive Descriptors for Structural and Statistical Analysis) is given. The description of the methodologies applied in CODESSA is followed by the presentation of the QSAR and QSPR models derived for eighteen molecular act...

A set of four phenylalanine analogues experiences diffusion retardation when transferred from phosphate-buffered saline into a peptide hydrogel of the same pH and ionic strength. The extent of retardation increases linearly with logP(oct), their lipophilicity.

High-resolution mapping of quantitative trait loci (QTL) in animals has proved to be difficult because the large effect sizes detected in crosses between inbred strains are often caused by numerous linked QTLs, each of small effect. In a study of fearfulness in mice, we have shown it is possible to fine map small-effect QTLs in a genetically heterogeneous stock (HS). This strategy is a powerful...