نتایج جستجو برای: locked nucleic acid
تعداد نتایج: 773157 فیلتر نتایج به سال:
Journal:
:Clinical Cancer Research
2009
Journal:
:BioMed Research International
2015
Journal:
:Journal of Visualized Experiments
2010
Journal:
:Journal of Computational Chemistry
2017
Journal:
:Nucleic Acids Research
2013
2015
Rita S Santos
George R Dakwar
Ranhua Xiong
Katrien Forier
Katrien Remaut
Stephan Stremersch
Nuno Guimarães
Sílvia Fontenete
Jesper Wengel
Marina Leite
Céu Figueiredo
Stefaan C De Smedt
Kevin Braeckmans
Nuno F Azevedo
Helicobacter pylori infects more than 50% of the worldwide population. It is mostly found deep in the gastric mucus lining of the stomach, being a major cause of peptic ulcers and gastric adenocarcinoma. To face the increasing resistance of H. pylori to antibiotics, antimicrobial nucleic acid mimics are a promising alternative. In particular, locked nucleic acids (LNA)/2'-OMethyl RNA (2'OMe) ha...
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