OBJECTIVE Resection of primary colorectal cancer is associated with enhanced risk of development of liver metastases. It was previously demonstrated that surgery initiated an early inflammatory response resulting in elevated tumour cell adhesion in the liver. Because reactive oxygen species (ROS) are shown to be produced and released during surgery, the effects of ROS on the liver vascular lini...

Ten percent of cirrhotic patients with severely compromised liver function will require a surgical procedure. This article reviews the surgical risk associated with liver damage and surgery. The most important prognostic factor is the degree of functional impairment of the liver. It is evaluated using the Child-Pugh score, which has limitations that have been partially overcome by the Model for...

OBJECTIVES Postoperative cognitive dysfunction is a serious complication that may be associated with increased mortality. Living-donor liver transplant includes major surgery for the donor. The purpose of this study was to evaluate preoperative and postoperative cognitive function of liver donors in living-donor liver transplant. MATERIALS AND METHODS In 102 patients who had hepatectomy for l...

This article reviews unresolved problems in the surgical treatment of primary and metastatic liver cancer ways to overcome them. The state affairs surgery calls for new patient-oriented rational tactics, use methods diagnosis malignant tumours, as well multidisciplinary therapeutic diagnostic approaches.

Presenter: Guergana Panayotova MD, MHS | Rutgers University Background: The precise impact of neoadjuvant chemotherapy for patients with intrahepatic cholangiocarcinoma (iCCA) remains unclear. While small, single center series suggest improved survival receiving followed by surgery, the overall to be elucidated. present study sought determine whether a multimodal treatment approach, including s...

Liver transplantation or hepatic is a procedure of replacing diseased liver with healthy liver. It needs cautious post-operative care including nutritional intervention. We present 65 year old patient underwent transplant due to acute failure. The patient’s diet history revealed daily intake carbohydrates and fats but inadequate protein intake. interventions were analyzed evaluated through hosp...

Recent studies have defined objective criteria for determining whether surgery is safe for patients with liver disease. Using these criteria, we may extend the benefit of surgery to more patients with liver disease without increasing the risk.

UNLABELLED Hepatocellular carcinoma (HCC) is a common cause of cancer-related death. Sorafenib prolongs survival of patients with advanced disease and is approved for the systemic treatment of unresectable HCC. It possesses antiangiogenic and antiproliferative properties by way of inhibition of the receptor tyrosine kinases vascular endothelial growth factor receptor 2 (VEGFR-2) and platelet-de...

Mutation in several factors and pathways leads to the development of hepatic cancer i.e. Wnt-β-Catenin Signalling Pathway , activation Insulin-Like Growth Factor (IGF) Pathway, The P13/PTEN/AKT, TP53 Tumour Suppressor Gene. Liver cirrhosis fatty liver predispose normal tissues fibrosis leading cancer. Excessive alcohol intake results inflammation proceeding ultimately carcinoma. Hepatocellular ...

Correction Contact me if this article is corrected. Citations Contact me when this article is cited. Topic collections Contact me when new articles are published in these topic areas. Intervention Other; Gastroenterology; Liver/ Biliary Tract/ Pancreatic Diseases; Cardiovascular Transplantation; Kidney Transplantation; Liver Transplantation; Transplantation, Cardiothoracic Surgery; Endocrine Su...