Objectives. To study the effects of various concentrations food additive E407a (semi-refined carrageenan) on metabolic activity fetal liver cells, splenocytes, and bone marrow cells. Material methods. Fetal liver, splenocytes cell cultures were incubated with at varying from 0 mg/ml to 10 for 24 hours (n=8). analyze this a colorimetric MTT assay was used. It is based ability viable, metabolical...

Liver cancer has a poor prognosis predominantly resulting from tumour heterogeneity and limited treatment options. The two predominant types of liver are Hepatocellular carcinoma (HCC) Intrahepatic Cholangiocarcinoma (iCCA). CD44v6, splice variant the hyaluronic acid receptor CD44, is marker for stem cells, known to impact formation metastasis in several cancers. expression CD44v6 dramatically ...

Objective(s): In this study, effects of encapsulated umbilical cord stem cells (UCSCs)-derived hepatocyte-like cells (HLCs) in high mannuronic alginate scaffolds was investigated on CCl4-induced acute liver failure (ALF) in rats. Material and Methods: UCSCs were encapsulated in high mannuronic alginate scaffolds. Then the UCSCs differentiated into HLCs for treatment of CCl4-induced ALF in rats....

Diclofenac, the anti-inflammatory drug, is found in natural water bodies all over the world. Toxicological researches of diclofenac report harmful effects on aquatic species even at low concentrations. The aim of present study was to determine whether diclofenac affected on the gills, liver and kidney of common carp (Cyprinus carpio). In order to evaluate toxic effects of diclofenac as NASIDs (...

background : human wharton’s jelly mesenchymal stem cells (hwjmscs) express liver-specific markers such as albumin, alpha-fetoprotein, cytokeratin-19, cytokeratin-18, and glucose-6-phosphatase. therefore, they can be considered as a good source for cell replacement therapy for liver diseases. this study aimed to evaluate the effects of various culture systems on the hepatocyte-specific gene exp...

Liver ischemia and reperfusion (IR) injury is the major complication of liver-related operations. Macrophage polarization has an essential effect on mechanism liver IR injury. Vitamin D receptor (VDR) been found to regulate macrophage alleviate Nevertheless, correlation between VDR in not clearly elucidated. knockout mice wild-type littermates underwent partial for 90 min 6 h. RAW264.7 cells we...

Three new Complexes of formula [pd(bpy)(R-NH-CSS)] Cl (where bpy is 2/2′- bipyridine, and R-NH-CSS is butylamine, hexylamine- and octyamine-dithiocabamate anion) have been synthesized by University of Sistan and Blachostan. These complexes have been characterized by spectroscopic methods such as ultraviolet-visible, infrared and 1H-NMR as well as conductivity measurements and chemical analysis....