نتایج جستجو برای: lithiumalanine interactions

تعداد نتایج: 387717  

2013
Bulus Adzu Kudirat Bola Mustapha Collen Masimirembwa Obiageri Obodozie Rukaiyatu Abdullahi Kirim Karniyus Shingu Gamaniel

OBJECTIVE To evaluate the effect of NIPRD-AM1 on CYP3A4 in order to generate clinically significant data for its safe and efficacious use. MATERIALS AND METHODS NIPRD-AM1 is a phytomedicine developed from aqueous root extracts of Nauclea latifolia Smith (Rubiaceae) for the treatment of uncomplicated malaria. The effect of NIPRD-AM1 on CYP3A4 was measured with and without the addition of NIPRD...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2014
Scott J Brantley Aneesh A Argikar Yvonne S Lin Swati Nagar Mary F Paine

Supported by a usage history that predates written records and the perception that "natural" ensures safety, herbal products have increasingly been incorporated into Western health care. Consumers often self-administer these products concomitantly with conventional medications without informing their health care provider(s). Such herb-drug combinations can produce untoward effects when the herb...

2017
Salih Kılıç Ahmet Çelik Hüseyin Altuğ Çakmak Abdülmecit Afşin Ahmet İlker Tekkeşin Gönül Açıksarı Mehmet Erdem Memetoğlu Fatma Özpamuk Karadeniz Ekrem Şahan Mehmet Hayri Alıcı Yüksel Dereli Ümit Yaşar Sinan Mehdi Zoghi

BACKGROUND The time in therapeutic range values may vary between different geographical regions of Turkey in patients vitamin K antagonist therapy. AIMS To evaluate the time in therapeutic range percentages, efficacy, safety and awareness of warfarin according to the different geographical regions in patients who participated in the WARFARIN-TR study (The Awareness, Efficacy, Safety and Time ...

2013
Jin GU Hai-Bin CHEN

Drug-drug interaction and herb-drug interaction have been frequently reported when patients take propofol in combination with other important clinical drugs or herbs. Intestinal bacteria-catalyzed biotransformation process might significantly change the properties of compounds, such as the efficiency, toxicity, and the pharmacokinetic behaviours. The present study aims to investigate whether th...

2017
José C.E. Serrano Anna Cassanyé

2016
Manish Yadav Pankaj Sharma Vandana Chaudhary

Journal: :Spatial and spatio-temporal epidemiology 2010
María-Eugenia Grillet Geraldine J Jordan Marie-Josée Fortin

Mosquito-borne disease spread might exhibit irregular epidemic fronts caused by ecological heterogeneity in the risk factors. To determine Plasmodium vivax infection spread in north-eastern Venezuela, we used the State Transition Index (STI) to detect the spatial locations of malaria incidence boundaries and their dynamics over time. Then, we evaluated the role of population size on disease per...

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