MOTIVATION There is a pressing need for improved proteomic screening methods allowing for earlier diagnosis of disease, systematic monitoring of physiological responses and the uncovering of fundamental mechanisms of drug action. The combined platform of LC-MS (Liquid-Chromatography-Mass-Spectrometry) has shown promise in moving toward a solution in these areas. In this paper we present a techn...

abstract polycyclic aromatic hydrocarbons (pahs) are classified as persistent and carcinogenic organic pollutants. pahs contamination has been reported in water. many of relevant regulatory bodies such as eu and epa have regulated the limit levels for pahs in drinking water. in this study, 13 priority polycyclic aromatic hydrocarbons (pahs) were determined in tap water samples of tehran and wat...

Partially coalified, structurally intact latex fibers found in a low rank coal were characterized by analytical methods. The latex fibers have a high sulfur content of approximately 10 percent. It has been proposed in previous studies, and it appears to be the case here, that the latex material has been “naturally” vulcanized during the early diagenetic period. Two fossilized latex samples reco...

Siderophores are thought to play an important role in iron cycling in the ocean, but relatively few marine siderophores have been identified. Sensitive, high throughput methods hold promise for expediting the discovery and characterization of new siderophores produced by marine microbes. We developed a methodology for siderophore characterization that combines liquid chromatography (LC) inducti...

In this article, selected examples of applications of liquid chromatography coupled to mass spectrometry are given. The examples include the analysis of i) impurities in manufactured, pharmaceutical or synthesis products, ii) polyphenols in natural products, and iii) phytohormones in plant extracts. Finally, examples of applications of molecular characterization via flow injection analysis by e...

Food, drugs, dyes, extracts, and minerals are all made up of complex elements, utilizing unidimensional chromatography to separate them is inefficient insensitive. This has sparked the invention several linked methods, each with distinct separation principles affinity for analyte interest. Multidimensional consists combination multiple techniques, great benefits at level efficiency, peak capaci...

Schizophrenia is a neuropsychiatric disorder affecting 1% of the world’s population. Due to a broad range of symptoms and wide heterogeneity, current therapeutic approaches in schizophrenia fail to treat all symptomatic manifestations of the disease. Therefore, new models that reproduce core pathological features of schizophrenia are needed for the elucidation of unidentified pathological disea...

This paper proposes an intelligent learning management system with load-balancing function based on Grid structure that allows for the replication of learning materials and balance of network traffic. The system consists of the Learning Management System (LMS) for processing basic data, learning data and learning records of learners, and the Learning Content Management Systems (LCMS) based on t...