In the past two decades there have been major advances in the development of liposomal drug delivery systems suitable for applications ranging from cancer chemotherapy to gene therapy. In general, an optimized system consists of liposomes with a diameter of approximately 100 nm that possess a long circulation lifetime (half-life >5 h). Such liposomes will circulate sufficiently long to take adv...

objective(s):tumor-associated antigen (taa) subunit-based vaccines constitute promising tools for anticancer immunotherapy. however, a major limitation in the development of such vaccines is the poor immunogenicity of peptides when used alone.the aim of this study was to develop an efficient vaccine delivery system and adjuvant to enhance anti-tumor activity of a synthetic her2/neu derived pept...

Liposomal targeted drug delivery makes it possible to achieve effective concentration in the target cell under various pathological conditions. The main advantage of liposomal particles is their biodegradability and immunological neutrality, which improves safety profile drugs. review provides information on composition liposomes: component membrane phospholipids, provide its strength protect f...

background: sustained release delivery system can reduce the dosage frequency and maintain the therapeutic level of drugs for a longer time. biodegradable, biocompatible and thermosensitive chitosan-beta-glycerophosphate (c-gp) solutions can solidify at body temperature and maintain their physical integrity for a longer duration. objectives: to develop a novel delivery system based on the integ...