نتایج جستجو برای: liothyronine
تعداد نتایج: 2794 فیلتر نتایج به سال:
CONTEXT The substitution of liothyronine (L-T3) for levothyroxine (L-T4) is commonly employed during thyroid hormone (TH) withdrawal in preparation for diagnostic and therapeutic interventions on thyroid cancer patients. Presently, only limited data are available on the L-T3 for L-T4 therapeutic substitution. Objective To characterize the pharmcodynamic equivalence of L-T3 and L-T4. DESIGN Ra...
Comparatively little is known about the interference in actions and metabolism of hormones by their appropriate analogues, though thyroxine has been studied in this regard more than have other hormones. One analogue which has been demonstrated by Maclagan et ~2. (1) to prevent the calorigenic effect of thyroxine is butyl+Ghydroxy-3,5-diiodobenxoate (BHDB). The mechanism of antagonism has not be...
The relationship between the binding of L-triiodothyronine (T3) to nuclear receptors and the induction of growth hormone synthesis was examined in cultured GH1 cells, a rat pituitary cell line. After 24 hr, T3 induced a maximal 4-fold increase in the rate of growth hormone wynthesis; the T3 concentration that induced a half-maximal increase was 0.22 nM. The biologic dose-response curve was shif...
We evaluated the effects of high ambient temperature and feed restriction in primiparous lactating sows. Females were exposed to either a constant thermoneutral (20 degrees C) or hot environment (30 degrees C). Lactating sows at 30 degrees C were given free access to feed (30AL; n = 12), and sows at 20 degrees C were restricted according to the feed intake recorded at 30 degrees C (20RF; n = 6)...
Extensive use of radioimmunoassay for routine measurement of serum thyroid hormones in paediatric thyroid disorders showed inconsistencies between laboratory results based upon adult criteria and clinical observation. To resolve this disparity, serum triiodothyronine (T3) and thyroxine (T4) levels were measured by radioimmunoassay in 354 healthy children aged between 3 weeks and 1 7 years. The ...
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