Phytophthora palmivora is a destructive plant pathogenic oomycete that has caused lethal diseases in wide range of hosts. It pan-tropical distributed pathogen can infect plants at all growth stages. Extensive studies have linked P. to severe several crops, such as black pepper, rubber, cocoa, and durian, causing global economic losses. This review covers the following topics depth: (i) phytopat...

BACKGROUND Parkinson's disease is a heterogeneous disorder where genetic factors may underlie clinical variability. Rapid eye movement sleep behavior disorder (RBD) is a parasomnia strongly linked to synucleinopathies, including Parkinson's disease. We hypothesized that SNCA variants conferring risk of Parkinson's disease would also predispose to an RBD phenotype. METHODS We assessed possible...

Objective: Borderline Personality Disorder (BPD) is a common psychiatric disease characterized by impulsiveness, aggressiveness and emotional instability. Self-injury and suicidal behaviours are common in these patients. Both genetic and environmental factors have been identified in the genesis and development of this disorder. This article is a review paper to study the genetic basis of the BP...

alzheimer's disease (ad) is the most common form of neurodegenerative disorders. memory loss in an alert person and impairment in the function of language, attention, perception, judgment or problem solving can occur in patients with ad. however, there are some medications in order to delay the debilitating aspects of the disease; but unfortunately, scientists could not found approaches to...

background: coronary artery disease (cad) is a multifactorial and heterogenic disease. recently, genome-wide association studies have reported that rs1333040 (c/t) and rs1004638 (a/t) single nucleotide polymorphisms (snps) in the 9p21 locus have very strong association with cad. this study aimed to examine these associations in southwest of iran. methods: blood samples were collected from 200 c...

conclusions the present findings showed that the ta7/7 promoter of ugt1a1 gene accounted for a considerable number of gilbert’s syndrome cases (11.3%). the studied variations had a significant effect on creatine phosphokinase and serum total bilirubin levels. results about 78.9% of the studied subjects had normal homozygous genotypes, and 21.1% were heterozygous for the gly71arg variation. in t...

alzheimer's disease (ad) is a genetically heterogeneous neurodegenerative disease and late-onset type (load) is the most common form of dementia affecting people over 65 years old. calhm1 (p86l) encodes a transmembrane glycoprotein that controls cytosolic ca2+ concentrations and aß levels and p86l polymorphism in this gene is significantly associated with load in independent case controls in a ...