odontogenic tumors contain a heterogeneous collection of lesions that are categorized from hamartomas to benign and malignant neoplasms of inconstant aggressiveness. odontogenic tumors are usually extraordinary with assessed frequency of short of 0.5 cases/100,000 population for every year. the lesions such as odontogenic tumors are inferred from the components of the tooth-structuring contrapt...

conclusions anesthetic management for ire of soft tissue deviates from standard anesthetic medical therapy in regards to depth of neuromuscular blockade and analgesic management during ire energy delivery. however, minor modifications in anesthesia management allow for a safe and efficient patient procedure. results during ire delivery, a deeper neuromuscular blockade is required to ensure that...

abstract carcinoid tumors are well differentiated neuroendocrine tumors with secretory components. these tumors are uncommon but the most common primary tumors of the distal small intestine. we present a rare terminal ileum carcinoid tumor presenting with a small bowel obstruction. a 65 years old man presented with intermittent, gen-eralized, dull and colicky abdominal pain accompanied with int...

Exophytic intramedullary tumors can look like extramedullary tumors on myelography, as in this case. Contrast-enhanced sagittal and axial MR shows the true origin of these tumors.

Elevated neoantigen load has been previously correlated with improved outcome and response to immune checkpoint blockade in various tumor types. In endometrial cancer, previous studies of neoantigen load prediction have shown that the hypermutated MSI and POLE-mutated tumors harbor significantly higher predicted neoantigen load compared to the hypomutated CN-low/endometrioid and CN-high/serous-...

Platelet-activating factor (PAF) plays an important role in the pathogenesis of several types of tumors. The biological effects of PAF are mediated by the PAF receptor (PAFR), which can be expressed by tumor cells and host cells that infiltrate the tumor microenvironment. In the present study, we investigated the role of PAFR expressed by leukocytes that infiltrate two types of tumors, one that...

BACKGROUND We have previously reported an array comparative genomic hybridization profile that identifies triple-negative breast cancers (TNBC), with BRCA1 dysfunction and a high sensitivity to intensified dose bifunctional alkylating agents. To determine the effect of conventional-dose chemotherapy in patients with this so-called BRCA1-like profile, clinical characteristics and survival were s...

introduction : fibrolamellar carcinoma (flc), a subtype of hepatocellular carcinoma (hcc), is a rare primary hepatic malignancy. several aspects of the clinical features and epidemiology of flc remain unclear since most literature on flc consists of case reports and small cases series with limited information on factors that affect survival. majority of the tumors occurred in patients less than...

Age and physiologic status, such as menopause, are risk factors for breast cancer. Less clear is what factors influence the diversity of breast cancer. In this study, we investigated the effect of host age on the distribution of tumor subtypes in mouse mammary chimera consisting of wild-type hosts and Trp53 nullizygous epithelium, which undergoes a high rate of neoplastic transformation. Wild-t...