With the complete sequencing of the human genome under way and the sequencing of complete microorganism genomes becoming commonplace, we have truly entered the era of large-scale DNA sequencing. Why now? As in some other data-rich areas of modern biology, for example, protein structure determination, it can be argued that the ratelimiting factors in increasing efficiency and throughput have bee...

Inserm, UMR-S 1144, 75006 Paris, France Service de psychiatrie adulte, pôle neurosciences, groupe hospitalier Saint-Louis-Lariboisière-Fernand Widal, AP–HP, 200, rue du Faubourg-Saint-Denis, 5475 Paris cedex 10, France UMR-S 1144, université Paris Descartes, 75006 Paris, France UMR-S 1144, université Paris Diderot, 75013 Paris, France Fondation FondaMental, 94000 Créteil, France Inserm U 1171, ...

the assessment of document qualities such as depth and objectivity. The primary purpose is to develop a qualitysensitive functionality, orthogonal to relevance, to select documents for an interactive question-answering system. The study consisted of two stages. In the classifier construction stage, nine document qualities deemed important by information professionals were identified and classif...

In the 2021 German federal election, Left Party suffered its worst electoral defeat ever. Although it hemorrhaged voters to all parties, losses Social Democrats and Greens were particularly large. this article, we examine reasons behind Die Linke’s poor performance. a number of factors may have played small roles, hypothesize that most important by far was Party’s failure distinguish itself in ...

The effect of different light qualities (white, blue, green, yellow and red light) on photosynthesis, measured as chlorophyll fluorescence, and the accumulation of photosynthetic pigments, proteins and the UV-absorbing mycosporine-like amino acids (MAAs) was studied in the red alga Porphyra leucosticta. Blue light promoted the highest accumulation of nitrogen metabolism derived compounds i.e., ...

Under typical viewing conditions, we can easily group materials into distinct classes (e.g., woods, plastics, textiles). Additionally, we can also make many other judgments about material properties (e.g., hardness, rigidity, colorfulness). Although these two types of judgment (classification and inferring material properties) have different requirements, they likely facilitate one another. We ...