Large historical databases, although intended to last for a long time, can become obsolete variety of reasons. In this essay these reasons are explored and used 'health check' the Historical Sample Netherlands (HSN). The HSN leaders examined their visionary qualities sense ownership, database its complementarity, versatility consistency. concludes that, despite challenges ahead, is sound mind b...

In haplorhine primates, when the effect of body weight is removed, brain weight is correlated with maximum recorded life-span. In this paper we have analyzed the relationships between volumes of specific brain structures and life-span. When the effect of body weight is removed, the volumes of many brain structures are significantly, positively correlated with maximum recorded life-span. However...

Reduction of food intake without malnourishment extends life span in many different organisms. The majority of work in this field has been performed in rodents where it has been shown that both restricting access to the entire diet and restricting individual dietary components can cause life-span extension. Thus, for insights into the mode of action of this intervention, it is of great interest...