Propositional modal provability logics like G and Grz have arithmetical interpretations where 2φ can be read as “formula φ is provable in Peano Arithmetic”. These logics are decidable but are characterised by classes of Kripke frames which are not first-order definable. By abstracting the aspects common to their characteristic axioms we define the notion of a formula generation map F(p) in one ...

The iron-binding protein lactoferrin (Lf) present in blood is metabolized by the liver. Isolated rat hepatocytes vigorously endocytose bovine Lf via recycling Ca2(+)-dependent binding sites, but the uptake of iron from Lf by hepatocytes has not been examined. In this study, isolated rat hepatocytes were incubated with radiolabelled bovine Lf (125I-Lf, 59Fe-Lf or 125I-59Fe-Lf) at 37 degrees C, t...

Logical frameworks have enjoyed wide adoption as meta-languages for describing deductive systems. While the techniques for representing object languages in logical frameworks are relatively well understood, languages and techniques for metaprogramming with them are much less so. This paper presents work in progress on a programming language called Rogue-Sigma-Pi (RSP), in which general programs...

LF has been designed and successfully used as a meta-logical framework to represent and reason about object logics. Here we design a representation of the Isabelle logical framework in LF using the recently introduced module system for LF. The major novelty of our approach is that we can naturally represent the advanced Isabelle features of type classes and locales. Our representation of type c...

A 20-day treatment with LF15-0195, a deoxyspergualine analogue, induced allograft tolerance in a fully MHC-mismatched heart allograft model in the rat. Long-term allografts displayed minimal cell infiltration with no signs of chronic rejection. CD4+ spleen T cells from tolerant LF15-0195-treated recipients were able to suppress in vitro proliferation of allogeneic CD4+ T cells and to transfer t...

Let X be a locally compact Hausdorff topological space, let V = ( v n , k ) ∈ N $\mathcal {V}=(v_{n,k})_{n,k\in {\mathbb {N}}}$ system of positive continuous functions on and φ self-map X. The composition operators C : f ↦ ∘ $C_\varphi f\mapsto \ f\,\circ\, \varphi$ the weighted function (LF)-spaces {V}C(X)$ 0 {V}_0C(X)$ resp.) (PLB)-spaces A {A}C(X)$ {A}_0C(X)$ are studied. We characterize whe...