BACKGROUND There is an increase in inflammatory and a reduction in anti-inflammatory cytokines in multiple sclerosis (MS). Considering the role of thyroid hormones in the development and regulation of both neural and immune systems, the aim of this study was to evaluate the effects of levothyroxine on serum concentrations of interleukin-10 (IL-10) and interferon gamma (IFN-γ) in animal models o...

Thyroid cancer is the most common endocrine malignancy, more frequently diagnosed in young women during childbearing age and approximately 10% of all thyroid cancers are diagnosed during pregnancy or in the early post-partum period. Thyroid cancer in young people has generally an excellent prognosis, and survival among women with thyroid cancer diagnosed during pregnancy may not differ from tha...

Cavitary lesions due to pulmonary tuberculosis are very rare in infants, although these may be found in older children and adolescents [1]. We report a six-month-old girl who presented with history of recurrent episodes of respiratory infections, failure to gain weight, rapid respiration and feeding difficulty since 3 months of age. Failure to thrive, respiratory distress, clubbing and decrease...

BACKGROUND The population of the UK is ageing. There is compelling evidence that thyroid stimulating hormone distribution levels increase with age. Currently, in UK clinical practice elderly hypothyroid patients are treated with levothyroxine to lower their thyroid stimulating hormone levels to a standard non-age-related range. Evidence suggests that mortality is negatively associated with thyr...

a study was conducted to evaluate the effects of blood pressure medications on index of liver damage in ascites incidence in broilers. a completely randomized experimental design with a 2×3 factorial arrangement (sex and feed additive), with 3 replicates of 12 birds, with 216 (108 male and 108 female) one-day-old (ross 308) was applied. feed additive includes control (without feed additive) lev...

Levothyroxine tablet overdose, can happen in children, because of unique physical nature the tablet. Although it has a benign course, systemic symptoms overdose may manifest few children. This cannot be predicted based on dose consumed or by thyroid function tests. Propranolol and steroid used for autonomic symptoms. Delayed manifestation occur, which needs follow up. In this report, we present...

The most common cause of apparent inefficiency or resistance to oral therapy with levothyroxine for hypothyroidism is nonadhesion. However, in some subjects in whom the control of hypothyroidism is extremely difficult, levothyroxine bioavailability defects should be considered. We report here the case of a 57-year-old woman with hypothyroidism that was well-controlled for the previous 6 years b...