abstract because of relation between digestive enzyme activity and feeding of insects that directly is in relation with the damage of insects; studying digestive enzyme systems is important in finding new control methods based on inhibiting digestive enzyme activity. recently using transgenic plants containing enzyme inhibitors is important in improving resistance of crops to pests because of s...

The current work reports adsorption of Ni(II) using Brassica botrytis leaves (BBL), leaves-activated carbon (BBL-AC), Lycopersicon esculentum peel (LEP) and peel-activated (LEP-AC). was tested in batch experiments by varying different parameters such as pH, initial metal ion concentration, temperature, adsorbent dosage, contact time. Thermodynamics kinetics investigations were performed for Ni ...

By supplying most organs of the body with metabolic substrates, the liver plays a central role in maintaining energy balance. Hepatic metabolism of glucose, fatty acids, and lipoproteins is disrupted in the leptin-deficient obese (Lep(ob)/Lep(ob)) mouse, leading to hyperglycemia, steatosis, and hypercholesterolemia. Microarray expression profiles were used to identify transcriptional perturbati...

Sexual size dimorphism is the consequence of differential expression of sex-biased genes related to feeding and growth. Leptin is known to regulate energy balance by regulating food intake. In order to investigate the molecular mechanism of sexual size dimorphism in yellow catfish (Pelteobagrus fulvidraco), the expression of leptin (lep) and its functional receptor (lepr) were detected during l...

Leptin is a fat hormone regulating energy homeostasis. Here, it is reported that the promoter and CpG island of the autosomal gene Leptin (LEP) is a tissue-specific differentially methylated region (T-DMR) and subject to dynamic methylation in human and mouse in vivo. Highly variable densities of cytosine methylation were detected by hairpin-bisulfite PCR among cells in human adipose tissue and...

Assembly of several inner membrane proteins-leader peptidase (Lep), a Lep derivative (Lep-inv) that inserts with an inverted topology compared with the wild-type protein, the phage M13 procoat protein, and a procoat derivative (H1-procoat) with the hydrophobic core of the signal peptide replaced by a stretch from the first transmembrane segment in Lep-has been studied in vitro and in Escherichi...

BACKGROUND Potential association of leptin (LEP) gene polymorphisms has been suggested in the processes leading to breast cancer initiation and progression. We investigated whether genetic variations in the LEP -2548G/A gene are associated with risk of breast cancer. METHODS This case-control study consisted of 100 breast cancer cases and 100 control subjects without breast cancer that matche...

INTRODUCTION Leptin (LEP) and its receptor (LEPR) participate in the immunological response during infection. LEP serum levels rise during sepsis. In patients with peritonitis, an insufficient elevation in serum LEP is associated with an increased risk of death. As gene variants of LEP and LEPR have been associated with diverse pathologic conditions, we explored the association of genetic polym...