Classical theories suggest that the surface area of the crystalline lens changes during accommodation while the lens volume remains constant. Our recent work challenged this view by showing that the lens volume decreases as the lens flattens during unaccommodation. In this paper we investigate 1) the magnitude of changes in the surface of the in vitro isolated cow lens during simulated accommod...

In Xenopus laevis tadpoles, wounding of the outer cornea failed to initiate lens regeneration. If both the outer and inner corneas were wounded or if the lens was dislocated, lens regeneration was initiated but failed to continue beyond stage III. However, lensectomy followed by re-implantation of the lens resulted in the regeneration of a fully differentiated lens in several cases, despite the...

Animals may synthesize antibodies capable of reacting with numerous lens proteins of their own eyes. Such antibodies may bathe the lens for prolonged periods, yet not produce lesions. However, disruption of the lens capsule in such animals, with leakage of lens substance, appears to restdt in an accentuated inflammatory response due to hypersensitivity mechanisms, although the data along these ...

The right lenses were removed from a group of chick embryos at five days of incubation. Each lens was replaced by two lenses from donors of the same age. The donor lenses were implanted so that their equatorial planes lay at right angles to the equatorial plane of the host lens which they replaced. These cases were studied at 14 days of incubation. The volume of such lens pairs became regulated...

PURPOSE A four-month extended wear clinical trial was conducted to compare the ocular effects of a high Dk Balafilcon A silicone hydrogel lens and a low Dk HEMA 38.6 per cent H20 soft lens. METHOD Twenty-four subjects who were adapted to daily wear of soft lenses wore a high Dk lens in one eye and a low Dk HEMA lens in the other eye for four months on an extended wear basis after one week of ...

Millions are rendered blind or exhibit visual impairment due to pathologies of the lens of the eye. Lens research therefore addresses the direct need to gain insights into the cellular and molecular basis of disease, but, moreover, serves as a valuable experimental system to answer fundamental biological questions. This themed issue showcases the scientific knowledge of the processes involved i...

The performance of an intraocular lens is determined by several factors such as the surgical technique, surgical complications, intraocular lens biomaterial and design, and host reaction to the lens. The factor indicating the biocompatibility of an intraocular lens is the behavior of inflammatory and lens epithelial cells. Hence, the biocompatibility of intraocular lens materials is assessed in...

purpose: to evaluate densitometry of crystalline lens after cxl procedure in keratoconic patients. methods: in a quasi-experimental study three-dimensional lens densitometry was performed by pentacam scheimpflug camera at base line and 6 months later. subject group contained patients with diagnosed progressive keratoconus who underwent cxl surgery (n = 40). control group contained aged-matched ...

MP20 is an intrinsic membrane protein previously identified in mammalian lens fiber cells. To identify a possible role for this protein in the lens, the distribution of MP20 and connexin46 has now been examined. Western immunoblotting with an anti-peptide antibody generated to the C-terminal 8 amino acids of MP20 confirmed the presence of this protein in the lens of several different mammalian ...

Two types of lenses can focus light: an optical lens using refraction phenomenon and a diffractive lens using diffraction phenomena. Table 1 shows the characteristics of each lens. The focal length of the diffractive lens is controlled by the structures of the lens, as mentioned in detail in Section 2.2. This suggests that the focal length of the diffractive lens is independent of refractive in...