نتایج جستجو برای: ldha

تعداد نتایج: 345  

2016

Biohydrogen is considered a promising and environmentally friendly energy source. Escherichia coli BW25113 hyaB hybC hycA fdoG frdc ldhA aceE has been previously engineered for elevated biohydrogen production from glucose. In this study, we show that this strain can also use biomass from oil palm frond (OPF) juice and sewage sludge as substrates. Substrate improvement was accomplished when hydr...

Journal: :Acta Crystallographica Section D Biological Crystallography 2015

2011
Jordan T. Newington Andrea Pitts Andrew Chien Robert Arseneault David Schubert Robert C. Cumming

Amyloid beta (Aβ) peptide accumulation in the brains of patients with Alzheimer's disease (AD) is closely associated with increased nerve cell death. However, many cells survive and it is important to understand the mechanisms involved in this survival response. Recent studies have shown that an anti-apoptotic mechanism in cancer cells is mediated by aerobic glycolysis, also known as the Warbur...

2016
Myriam M. Chaumeil Marina Radoul Chloé Najac Pia Eriksson Pavithra Viswanath Michael D. Blough Charles Chesnelong H. Artee Luchman J. Gregory Cairncross Sabrina M. Ronen

Metabolic imaging of brain tumors using (13)C Magnetic Resonance Spectroscopy (MRS) of hyperpolarized [1-(13)C] pyruvate is a promising neuroimaging strategy which, after a decade of preclinical success in glioblastoma (GBM) models, is now entering clinical trials in multiple centers. Typically, the presence of GBM has been associated with elevated hyperpolarized [1-(13)C] lactate produced from...

2015
Sergio Arrabal Miguel Angel Lucena Miren Josune Canduela Almudena Ramos-Uriarte Patricia Rivera Antonia Serrano Francisco Javier Pavón Juan Decara Antonio Vargas Elena Baixeras Mercedes Martín-Rufián Javier Márquez Pedro Fernández-Llébrez Baukje De Roos Pedro Grandes Fernando Rodríguez de Fonseca Juan Suárez Vasu D. Appanna

Cannabinoid CB1 receptors peripherally modulate energy metabolism. Here, we investigated the role of CB1 receptors in the expression of glucose/pyruvate/tricarboxylic acid (TCA) metabolism in rat abdominal muscle. Dihydrolipoamide dehydrogenase (DLD), a flavoprotein component (E3) of α-ketoacid dehydrogenase complexes with diaphorase activity in mitochondria, was specifically analyzed. After as...

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