Cardiovascular parameters such as arterial blood pressure (ABP) and heart rate display pronounced circadian variation. The present study was performed to detect whether there is a circadian periodicity in the regulation of cerebral perfusion. Normotensive Sprague-Dawley rats (SDR, approximately 15 wk old) and hypertensive (mREN2)27 transgenic rats (TGR, approximately 12 wk old) were instrumente...

Digital replantation has recently become a common treatment method, and improvements in surgical techniques have increased its success rate.1 However, the overall failure rate remains a significant issue. Appropriatemeasurement of blood flow in transplanted tissue is important to prevent critical circulation failure. Of the various modalities advocated for postoperative monitoring of blood flow...

The heart activity is clearly evaluated in this study by analyzing spectral or frequency components of three Biosignals such as ECG, PPG and blood perfusion signal. This study is done with several healthy human subjects who are totally free from any type of cardiovascular diseases. ECG and PPG recordings were performed with electrode lead set and pulse transducer respectively connected to the s...

Pressure-induced vasodilation (PIV) is a mechanism whereby skin blood flow increases in response to progressive locally applied pressure. Skin blood flow in response to applied pressure decreased early in diabetic patients as a result of vascular and/or neural impairment. This study was designed to determine the effect of vascular changes on PIV in 1-week streptozotocin-induced diabetic mice. W...

The Linked Data Fragment (LDF) framework has been proposed as a uniform view to explore the trade-offs of consuming Linked Data when servers provide (possibly many) different interfaces to access their data. Every such interface has its own particular properties regarding performance, bandwidth needs, caching, etc. Several practical challenges arise. For example, before exposing a new type of L...

Iontophoresis was used for a non-invasive administration of the agonist histamine. Flares and weals areas were measured after 1%, 0.01% and 0.0001% histamine solution iontophoresis (30 s, 1.4 mA/cm2). There was no clear-cut correlation between area and concentration. 0.0001% histamine solution iontophoresis induced only a vanishing redness. When a typical weal developed ( 1% and 0.01% histamine...

We tested the hypothesis that cyclooxygenases (COXs) or COX products inhibit nitric oxide (NO) synthesis and thereby mask potential effects of NO on reactive hyperemia in the cutaneous circulation. We performed laser-Doppler flowmetry (LDF) with intradermal microdialysis in 12 healthy volunteers aged 19-25 yr. LDF was expressed as the percent cutaneous vascular conduction (%CVC) or as the maxim...

We measured detailed regional deposition patterns of inhaled particles in healthy adult male (n = 11; 25 +/- 4 yr of age) and female (n = 11; 25 +/- 3 yr of age) subjects by means of a serial bolus aerosol delivery technique for monodisperse fine [particle diameter (Dp) = 1 micron] and coarse aerosols (Dp = 3 and 5 micron). The bolus aerosol (40 ml half-width) was delivered to a specific volume...

The screening of adsorbents (zeolites, MOFs, ACs, etc) requires the measurement adsorption equilibria and kinetics at milligram scale. In this regard, a volumetric apparatus (constant volume variable pressure – batch adsorber) has been developed for studying sorption. Its validation was accomplished by carbon dioxide (CO2), methane (CH4) nitrogen (N2) sorption CO2 on commercial binder-free 4A z...

the phenomena of extensive air shower (eas) are produced by the collision of primary cosmic rays (cr) with energy more than ev with the atmospheric molecules. as a result the electron and muon components (cascades) of eas develop through the air.  the study of such cascades gives important information about the primary cr mass composition as well as its astrophysical origin models. one of the e...