On behalf of the Organizing and Program Committees, the General and Program Chairs warmly welcome all the participants to the 16th IEEE Latin-American Test Symposium (LATS2015). This year the conference is held in Puerto Vallarta (Mexico). LATS, (previously named Latin-American Test Workshop LATW) is a recognized forum for test and fault tolerance professionals and technologists from all over t...

Emerging evidence suggests that the proapoptotic kinase mammalian sterile 20-like kinase 2 (MST2) acts in a novel tumor suppression pathway. Recently, we showed that Raf-1 kinase sequesters and inhibits MST2 and that this event is critical for Raf-mediated cell survival. In this review, we summarize Raf control of MST2 and we outline a novel pathway involving the downstream effector proteins Sa...

Hippo signalling pathway plays a crucial role in tumorigenesis and cancer progression. In this work, we identified an N-aryl sulphonamide-quinazoline derivative, compound 9i as anti-gastric agent, which exhibited potent antiproliferative ability with IC50 values of 0.36 μM (MGC-803 cells), 0.70 (HCT-116 1.04 (PC-3 0.81 (MCF-7 respectively inhibited YAP activity by the activation p-LATS. Compoun...