During sea urchin embryogenesis, the skeleton is produced by primary mesenchyme cells (PMCs). PMCs undergo a sequence of morphogenetic behaviors that includes ingression, directed migration, and cell-cell fusion. Ultimately, PMCs deposit the calcite-containing biomineral that forms the endoskeleton of the late embryo and early larva. The endoskeleton has a stereotypical structure and is the maj...

the pathogenetic mechanism of nasal polyps remains unknown, although allergy has been cited as an important factor in the etiology of nasal polyposis. currently there is no definite histological criterion for differentiation of allergic from inflammatory nasal polyp. however, in a few studies, tissue eosinophil count has been used for this. this study aimed to find out the agreement rate of ski...

Baylisascaris procyonis is a roundworm of the raccoon found primarily in North America but also known to occur in other parts of the world including South America, Europe, and Japan. Migration of the larvae of this parasite is recognized as a cause of clinical neural larva migrans (NLM) in humans, primarily children. It is manifested as meningoencephalitis associated with marked eosinophilia of...

I read with interest the demonstration by Volbeda et al that clinical asthma control associates significantly with ‘lower activated eosinophil numbers in the bronchial wall, yet only weakly with sputum eosinophils’. I was particularly intrigued by the online supplemental information: ‘EPX staining showed widely spread distribution of eosinophilic granules, not necessarily in close proximity to ...

Procaterol inhibits IL-1band TNF-a-mediated epithelial cell eosinophil chemotactic activity. S. Koyama, E. Sato, T. Masubuchi, A. Takamizawa, K. Kubo, S. Nagai, T. Isumi. #ERS Journals Ltd 1999. ABSTRACT: Theophylline inhibits eosinophilic infiltration into the bronchial wall. It is unknown whether this is mediated by a cyclic adenosine monophosphate (c-AMP) dependent reduction in eosinophil ch...

Eosinophils are bi-lobed, multi-functional innate immune cells with diverse cell surface receptors that regulate local and inflammatory responses. Several infectious diseases triggered their build up in the blood tissues. The mobilization of eosinophils into lungs is regulated by a cascade processes guided Th2 cytokine generating T-cells. Recruitment essentially leads to characteristic response...

Figure 1. Cutaneous larva migrans on the left foot of a 36-year-old woman Diagnosis: Cutaneous larva migrans. Cutaneous larva migrans, also known as " creeping eruption, " is caused by larvae of the cat and dog hookworm. It is characterized by serpiginous, reddened, elevated, pruritic skin le-sions usually caused by Ancylostoma braziliense [1]. It occurs in warmer climates and is one of the mos...

inflammation in asthma and chronic obstructive pulmonary disease. Ann NY Acad Sci 2003; 992: 218–230. 18 Joos G, Pauwels R, Van Der Straten M. The effect of inhaled substance P and neurokinin A on the airways of normal and asthmatic subjects. Thorax 1987; 42: 779–783. 19 Wiedermann FJ, Kahler CM, Reinisch N, et al. Induction of normal human eosinophil migration in vitro by substance P. Acta Hae...