introduction: a large body of evidence points to oxidative stress as prime candidate mediating the behavioral impairments and memory deficits in alzheimer's disease (ad). it has been demonstrated that hyperoxia preconditioning activates complex endogenous neuroprotective mechanisms including an increase in capacity of antioxidant defence mechanisms. the aim of this study was to investigate...

introduction: intracerebroventricular (i.c.v.) injection of streptozotocin (stz) to rodents has been reported as an appropriate model for sporadic dementia of alzheimer's type (sdat), characterized by a progressive impairment of memory. however, very little or nothing is known about non-cognitive behavioral effects in the stz model. this study was carried out in order to show the protectiv...

Background and Objective: It is well known that stress and glucocorticoid, modulate memory processing, though the result is completely dependent on the time of stress induction. This study investigated the effect of acute corticosterone administration on memory retrieval of recent and remote memory in a 4 trials/day (low- intensity learning) or 8 trials/ day (high- intensity learning) Morris wa...

iranian traditional medicine (itm) describes a kind of dementia with similar signs and symptoms of alzheimer’s disease (ad). it explains the pathology of dementia with cold intemperament of the brain, which means that the brain is colder than its healthy form. itm strategy for treatment of dementia is to heat the brain up by medical “hot” herbs. nepeta menthoides (nm) is one of these “hot” herb...

Background: Previous researches have provided contradictory results about on working memory performance after the coronary artery bypass graft (CABG). In addition, studies have focused on the elderly community. For this reason and with regard to the importance and direct effects of working memory on the quality of life human. This study was designed to compare working memory of young CABG patie...

modern neuroscientific research help to solve the impotent challenge in curriculum design and teaching for enhancing students’ ability to organize information in a way that makes it efficient in response to an appropriate context such as problem solving and critical thinking via knowing about the mechanism of different type of memories especially long term memory. at first, we should to clarify...

Objective(s): Behavioral and neuroimaging studies have shown that transcranial direct current stimulation, as a non-invasive neuromodulatory technique, beyond regional effects can modify functionally interconnected remote cortical and subcortical areas. In this study, we hypothesized that the induced changes in cortical excitability following the application of cathodal or anodal tDCS over the ...

abstract background and objective: according to the importance of learning and memory in the human life and also unavoidable neural degeneration due to aging, finding new compounds (drugs) against this process is valuable. however, there are many recommendations for herbal medicine and constituents which encouraged us to examine a candidate plant zingiber officinalis for the mentioned purpose. ...

Background. Tinospora cordifolia, an Indian medicinal plant, has been reported to have beneficial effects on disorders like peptic ulcer, hepatobiliary disorders, rheumatism, infectious diseases etc. It enhances cognition in normal rats and successfully overcomes cyclosporine induced memory deficit. Methods. Thirty healthy volunteers of age 18-30 years received Tinospora cordifolia (500 mg of p...

there are evidences in both animal and human studies which show that exercise has beneficial effects on the central nervous system and cognition. so, the aim of this study was to investigate the effect of resistance exercise on memory and probable mechanisms of this effect (i.e. neurotrophic factors) in sedentary students. 30 sedentary students (mean age, 23.8±1.6 yr) were randomly divided into...