Treatment of 1-(5-bromo-2-chloro-6-methylpyrimidin-4-yl)-1-methylhydrazine with dimethylthiocarbamoylchloride gave 7-chloro-N,N,1,5-tetramethyl-1H-pyrimido[4,5-e][1,3,4]thiadiazin-3-amine in basic acetonitrile. The latter compounds were reacted with secondary amines in boiling ethanol to afford the related 7-amino derivatives.

The crystal structures of di-μ-chlorobis[2-(5-methyl-pyridin-2-yl-κN)phenyl-κC(1)] diplatinum(II) (1) and chloro(N,N-dimethylformamide-κO)[2-(5-methyl-pyridin-2-yl-κN)phenyl-κC(1)]platinum(II) (2) have been determined by means the X-ray diffraction. Both complexes cocrystallize in monoclinic space group C2/c with a = 39.5457(18) Å, b 7.2482(4) c 21.2269(10) Å β 121.460(2)°. asymmetric unit cons...

In this study, we examine macrocyclic compounds to determine whether they can provide a safer replacement and stable complex for BPA in thermochromic dyes. To achieve objective, series of compounds, Methyl-N-benzylhexahomotriazacalix[3]arene (MeAC3), p-Chloro-N-benzylhexahomo-triazacalix[3]arene (ClAC3), ?-Cyclodexdrin (?-CD), ?-Cyclodexdrin (?-CD), p-tert-Butylthiacalix[4]arene (TC4), Calix[4]...

A straightforward, one-pot procedure has been developed for the synthesis of bis-cyclometalated chloro(methyl)platinum(IV) complexes with a wide variety of heteroaromatic ligands of the 2-arylpyridine type. The new compounds exhibit phosphorescent emissions in the blue to orange colour range and represent the most efficient Pt(IV) emitters reported to date, with quantum yields up to 0.81 in flu...

alkaline complexes by X-ray crystallography,8) Seyeral studies on the chemical modification of the monensin skeleton have been reported, either on the Ci-Cs carboxylic moiety,9・iO) or at the C,,-hydroxyl group,ii) fo11owing the isolation of antibiotics X-14667A and Bi2) (monensin C26-phenethyl urethans). We have shown that the C26-chloro-4 phenyl urethan derivative had a transport selectivity, ...

Aryl sulfotransferase IV (EC 2.8.2.1), purified to homogeneity from male rat liver, catalyzes the sulfation of a variety of substituted phenols, including catecholamines, tyrosine esters, and peptides containing NH2-terminal tyrosine residues. An investigation of the mechanism of the enzyme was carried out using 2-chloro-4-nitrophenol as a model substrate. Kinetic, inhibition, and binding studi...

The proton-ligand and metal-ligand stability constants of the complexes of Cu(II), Ni(II),Co(II) with 1-Benzothiazol2-yl-3-(2-hydroxy phenyl)-5-(4-methoxy phenyl) pyrazoline (L), 1-Benzothiazol-2-yl-3-(2-hydroxy phenyl)-5-phenyl pyrazoline (L), 1-Benzothiazol-2-yl-3-(2-hydroxy phenyl)-5-(4-chloro phenyl) pyrazoline(L), 1-Benzothiazol-2-yl3-(2-hydroxy-5-methyl phenyl)-5-(4-methoxy phenyl) pyrazo...