In AIDS the onset of the ocular dry syndrome, characterized by lacrimal hyposecretion and deterioration of the corneal and conjunctival epithelium, generally accompanies the clinical aggravation of immunodepression. The study of serum and lacrimal proteins contributes to our knowledge of the pathophysiology of this syndrome. The lacrimal clearance of albumin indicates changes in the permeabilit...

The lacrimal gland plays an important role in maintaining a homeostatic environment for healthy ocular surfaces via tear secretion. Dry eye disease, which is caused by lacrimal gland dysfunction, is one of the most prevalent eye disorders and causes ocular discomfort, significant visual disturbances, and a reduced quality of life. Current therapies for dry eye disease, including artificial tear...

Three cases of unilateral epiphora following an attack of chickenpox were studied. Each patient was a child who was in good health prior to the onset of the attack. During the illness each had ocular symptoms suggesting local infection from the virus. A dacryocystogram revealed obstruction of the common canaliculus in each case caused by a fibrotic scar. All cases responded to appropriate surgi...

OBJECTIVE To compare the efficacy of external dacryocystorhinostomy (DCR) with and without intraoperative application of mitomycin-C in patients with chronic dacryocystitis. STUDY DESIGN An experimental study. PLACE AND DURATION OF STUDY Department of Ophthalmology, Bahawal Victoria Hospital (BVH), Bahawalpur, from September 2009 to December 2010. METHODOLOGY One hundred and sixty patient...

In this paper we describe research that applies educational datavisualization and data mining techniques in an Adaptive Exploratory eLearning Environment called the Adaptive eLearning Platform. Using a novel visualization tool called the Solution Trace Graph, we were able to visualize student interactions and thus gain insights that led to the refinement of the intelligently adapted remediation...

Oncocytoma of the lacrimal sac is a rarely encountered clinical entity. We report the case of a 72-year-old female patient who was diagnosed to have bilateral nasolacrimal duct obstruction during a pre-cataract surgery screening. Subsequently, she underwent bilateral dacryocystectomy. Histopathological examination of the left lacrimal sac revealed a tumour composed of acini lined by oncocytic c...

Background and Objectives: To review our experience with lacrimal sac tumors in an effort to identify features, to evaluate the results of various methods of management, and to compare our data with previous studies. Methods: We reviewed the medical records of all patients with lacrimal sac tumors who were managed in our institution between January 1990 and December 2015. The pre-operative clin...

Commensal bacteria play an important role in the formation of the immune system but their role in the maintenance of immune homeostasis at the ocular surface and lacrimal gland remains poorly understood. This study investigated the eye and lacrimal gland phenotype in germ-free and conventional C57BL/6J mice. Our results showed that germ-free mice had significantly greater corneal barrier disrup...

Lacrimal scintigraphy (LS) was performed on asymptomatic lacrimal drainage systems and the results were evaluated to understand the physiology of lacrimal drainage. It was found that a physiological obstruction can exist at the level of the nasolacrimal duct in normal asymptomatic individuals, and it is suggested that this obstruction is due to the resistance offered by the valve of Hasner, whi...

This was an unusual case of lacrimal sac compression by an anterior ethmoidal mucocele presenting as a late complication of a dacryocystorhinostomy (DCR) that was jointly managed by ophthalmic and ENT surgeons via an endoscopic approach. A 22-year-old lady presented with a 12-month history of a painless lump in her left medial canthus area and a 6-month history of left intermittent epiphora. Sh...