BACKGROUND Infection with a virulent Helicobacter pylori strain is associated with gastric mucosal damage and the increased risk of gastric cancer. AIMS To examine the characteristics of host gastric mucosal responses in patients with gastric cancer, histological grade of gastritis, gastric epithelial apoptosis, and proliferation were studied. METHODS Thirty two patients with early gastric ...

BACKGROUND One of the major morphologic characteristics of hepatitis B is a hepatocellular regeneration which is induced by massive hepatocyte necrosis and associated with proliferative activity of hepatocytes. The purpose of this study is to document the proliferative activity of hepatocytes in various types of hepatitis B by immunohistochemical staining for proliferative cell nuclear antigen-...

Accepted for publication 20 June 1996 Abstract Background and Aims-It has been reported that eradication of Helicobacter pylon improves fold width in H pylon associated enlarged fold gastritis. The aim of this study was to clarify the mechanism offold thickening in this condition. Patients and Methods-In eight patients with enlarged fold gastritis and 13 patients without enlarged folds, the pre...

It has previously been shown that longterm administration of insulin-like growth factor-I (IGF-I) or the analogue Long R3 IGF-I (LR3IGF-I) selectively stimulate growth of the gastrointestinal tract in gut resected, dexamethasone treated, and normal rats. In this study, the short-term effects of IGF-I administration on intestinal proliferation have been investigated. Female rats (110 g, five-six...

In technical drawings and medical drawings/maps it is often common to explain certain features of the drawing by blocks of text that are arranged on its boundary. Bekos et. al. introduced the term boundary labelling to describe this special type of labelling and presented algorithms for automatic boundary labelling. BLer is a prototype tool aiming to automate the boundary labelling process. It ...

For positive integers k and d ≥ 2, a k-S(d, 1)-labelling of a graph G is a function on the vertex set of G, f : V (G) → {0, 1, 2, · · · , k− 1}, such that |f(u)− f(v)|k ≥ { d if dG(u, v) = 1; 1 if dG(u, v) = 2, where |x|k = min{|x|, k − |x|} is the circular difference modulo k. In general, this kind of labelling is called the S(d, 1)-labelling. The σdnumber of G, σd(G), is the minimum k of a k-...

We describe a decision analytic, structured approach for developing environmental indexes ensuring them to be explicit and problem specific. The indexes are used for setting and communicating targets related to products’ environmental performance. Two index models are the fixed model based on the prevailing tradition, where announced targets must be met in every impact category, and the flexibl...

Appendiceal carcinoids are the most frequent tumors arising from appendix, comprising between 32 and 57% of all appendiceal tumors. The gross appearance appendix showed perforation at tip with 30 ml peri-appendicular collection. On histopathological examination, carcinoid tumor on was found cells arranged in tubules, acini nests infiltrating muscularis propria sub serosa. Perineural vascular in...

Human linear chromosomes are capped by specialized DNA-protein structures called telomeres. The present study analysed the telomerase activity, hTERT protein and telomere length in meningiomas and gliomas in relation to their WHO grading. Fifty-three freshly dissected tumour biopsies were analysed for telomerase activity, hTERT protein expression and telomere length. Telomerase activity was exa...

BACKGROUND The eutopic endometrium in a woman suffering from adenomyosis is known to be biologically different from that of healthy women. The aim of this study was to examine the apoptosis and proliferation of eutopic endometrium from women with adenomyosis. METHODS We enrolled 23 women with adenomyosis (study group) and 21 without (control group). Eutopic endometrium was obtained and separa...