The safety of bowel-cleansing agents is an important issue in clinical practice, especially in patients with chronic diseases. Although the safety and efficacy of polyethylene glycol (PEG) has been investigated in many studies, few studies on PEG plus ascorbic acid exist. In this study, we compared the safety of 2 bowel-cleansing agents for patients with liver cirrhosis: 2-liter PEG (2 L PEG) p...

The effects of L-ascorbic acid (LAA) on the in vitro growth of human leukemic colony-forming cells (L-CFC) were analyzed for all acute nonlymphocytic leukemia patients from whom bone marrow aspirates were received by this laboratory for cell culture study. Among 259 cases, 163 could be directly evaluated for LAA effect. L-CFC growth enhancement was noted in 53 (33%) and suppression in 28 (17%),...

Ascorbic acid (vitamin C) has major effects on the intestinal uptake and utilisation of Fe in humans. The objective of the present study was to investigate the impact of Fe on the acquisition of ascorbic acid. The strategy was to study the cellular uptake and transport of ascorbic acid in the presence of Fe and also to observe the expression of the Na-dependent vitamin C transporter 1 (SVCT1) p...

BACKGROUND Researchers suspect that the accepted adequate ascorbic acid plasma concentration is not being met even after dietary intake of the recommended amount of vitamin C. Current dietary intake recommendation in Poland is 60 mg per day for women and 75 mg per day for man (EAR), while in Western Europe and North America is higher and amounts to 75-90 mg per day. OBJECTIVE The paper aimed ...

BACKGROUND Both resveratrol and vitamin C (ascorbic acid) are frequently used in complementary and alternative medicine. However, little is known about the underlying mechanisms for potential health benefits of resveratrol and its interactions with ascorbic acid. METHODS The antioxidant enzymes heme oxygenase-1 and paraoxonase-1 were analysed for their mRNA and protein levels in HUH7 liver ce...

Among the most important problems of pistachio are physiological disorders such as fruit abscission and production of blank nuts. Environmental stresses and inadequate nutrition during flowering time have increased these problems in recent years. In order to evaluate the effects of foliar treatments with polyamines and other compounds (amino acids and ascorbic acid) on quantitative and qualitat...

The conversion of glucose-l-Cl4 to ascorbic acid-6-Cl4 and uniformly labeled glucose-Cl4 to uniformly labeled ascorbic acid-Cl4 in the Chloretonestimulated albino rat has been demonstrated (1, 2). To provide further evidence for a direct conversion of glucose to ascorbic acid and to eliminate pathways similar to that suggested by Bidder (3) for glucuronic acid formation, glucose-6-Cl4 has been ...

Changes in quality, total ascorbic acid, reduced ascorbic acid and dehydroascorbate in fresh cut ‘Selva’ strawberries (Fragariu x anana~~a Duch.) held for 7 days and ‘Fuyu’ persimmons (Diospyros kuki L.) held for 8 days at 5°C in air or controlled atmospheres were evaluated. Various atmospheres had significantly different effects on the color, pH, and titratable acidity of the fruits. The two f...

Hypertension is associated with low plasma ascorbic acid levels and impaired endothelial function. Recent evidence suggests that increased vascular oxidative stress contributes to the pathophysiology of endothelial dysfunction and hypertension. We recently showed that chronic oral ascorbic acid therapy lowers blood pressure in hypertensive patients. We hypothesized that it would also improve en...