Received 12 December 2013 Accepted 24 June 2014 Laboratory of Veterinary Pathology, School of Veterinary Medicine, Azabu University, 1-17-71 Fuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan Den-enchofu Animal Hospital, 2-1-3 Denenchofu, Ota-ku, Tokyo 145-0071, Japan Laboratory of Molecular Biology, School of Veterinary Medicine, Azabu University, 1-17-71 Fuchinobe, Chuo-ku, Sagamihara, ...

Yoshino Minoura, Hiroshi Onimaru, Kamon Iigaya Ikuo Homma, Youichi Kobayashi The Department of Medicine Division of Cardiology, Showa University School of Medicine, 1-5-8 Hatanodai Shinagawa-ku Tokyo Japan The Department of Physiology, Showa University School of Medicine, 1-5-8 Hatanodai Shinagawa-ku Tokyo Japan The Department of Internal Medicine, Keio University School of Medicine, 35 Shinano...

Department of Computer Science, Graduate School of Science and Engineering, Waseda University, 17 kikui-cho, Shinjuku-ku, Tokyo, 162-0044, Japan Computational Biology Research Center, National Institute of Advanced Industrial Science and Technology, Aomi-Frontier 17F, 2-43 Aomi, Koto-ku, Tokyo, 135-0064, Japan 3 Pharma Design inc., Haseko Hatchobori Build, 2-19-8 Hatchobori, Chuo-ku, Tokyo, 104...

∗1Faculty of Science and Engineering, Chuo University 1-13-27 Kasuga, Bunkyo-ku, Tokyo 112-8551, Japan E-mail: [email protected] ∗2Recruit Marketing Partners, Co., Ltd. 1-9-2 Marunouchi, Chiyoda-ku, Tokyo 100-6640, Japan ∗3Research Organization of Science and Technology, Ritsumeikan University 1-1-1 Nojihigashi, Kusatsu-shi, Shiga 525-8577, Japan ∗4Department of Neuropsychiatry, Keio Uni...

Keisuke Fujii 2, 3, 4 and Kohei Nakajima 4, 5 Photon Science Center, Graduate School of Engineering, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-8656, Japan The Hakubi Center for Advanced Research, Kyoto University, Yoshida-Ushinomiya-cho, Sakyo-ku, Kyoto 606-8302, Japan Department of Physics, Graduate School of Science, Kyoto University, Kitashirakawa Oiwake-cho, Sakyo-ku, Kyo...

Takaomi C. Saido,* Takeshi Iwatsubo,t David M. A. Mann,$ Hiroyuki Shimada,§ Yasuo Ihara,I] and Seiichi Kawashima* *Department of Molecular Biology Tokyo Metropolitan Institute of Medical Science Honkomagome, Bunkyo-ku, Tokyo Japan 1Department of Neuropathology and Neuroscience Faculty of Pharmaceutical Sciences University of Tokyo Hongo, Bunkyo-ku, Tokyo Japan tDepartment of Pathological Scienc...

M. Goto, O. Abe, S. Inano, T. Miyati, N. Hayashi, S. Aoki, H. Mori, H. Kabasawa, K. Ino, K. Yano, K. Iida, K. Mima, and K. Ohtomo Radiological Technology, University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan, Radiology, University of Tokyo, Bunkyo-ku, Tokyo, Japan, Graduate School of Medical Science, Kanazawa University, odateno, Kanazawa, Japan, Computational Diagnostic Radiology and Preventi...

Environmental Science Research Laboratory, Central Research Institute of Electric Power Industry, 1646 Abiko, Abiko, Chiba 270-1194, Japan Faculty of Environmental Earth Science, Hokkaido University and CREST-JST, North 10 West 5, Kita-ku, Sapporo, Hokkaido 060-0810, Japan Graduate School of Environmental Science, Hokkaido University, North 10 West 5, Kita-ku, Sapporo, Hokkaido 060-0810, Japan ...

Staphylococcus aureus is the most common bacterium present in upper respiratory tract, and the toxins it produced are involved in allergic inflammation pathogenesis. In this study, we investigated the clinical significance of IgE in association with staphylococcal superantigens in allergic asthma with rhinitis (BAwAR) and allergic rhinitis alone (AR). We recruited 100 patients with BAwAR (group...

Radiotherapy and chemotherapy are effective cancer treatments due to their ability to generate DNA damage. The major lethal lesion is the DNA double-strand break (DSB). Human cells predominantly repair DSBs by non-homologous end joining (NHEJ), which requires Ku70, Ku80, DNA-PKcs, DNA ligase IV and accessory proteins. Repair is initiated by the binding of the Ku heterodimer at the ends of the D...