Injuries to the extensor mechanisms of the fingers can be career-ending in professional athletes if not treated appropriately. We identified 8 professional athletes who underwent 11 direct metacarpophalangeal joint extensor mechanism repairs including centralization of the extensor tendon and sagittal band repair between 1989 and 1994. Success of the operative procedure was determined by the at...

Key Points  Loss or injury of pad tissue, despite an otherwise normal limb, can result in complete loss of limb function, so preserving pad function is critical for most small animals.  Skin around the pad may in some cases be able to adapt to function similar to pad tissue but it is generally accepted that adjacent skin is not a suitable replacement for lost pad tissue, particularly in activ...

Poland officially the republic of Poland, is a country in Central Europe. The total area of Poland is 312,679 square kilometres (120,726 sq mi), making it the 9th largest in Europe. Poland has a population of over 38.5 million people [1]. Polish is the official language. It is becoming an interesting location for research and development investments [1]. Many scientists and researchers originat...

OBJECTIVES The purpose of this study was to determine the association of family history of peripheral artery disease (PAD) with PAD prevalence and severity. BACKGROUND PAD is a significant public health problem. Shared genetic and environmental factors may play an important role in the development of PAD. However, family history of PAD has not been investigated adequately. METHODS The San D...

Lower extremity peripheral arterial disease (PAD) is prevalent in the Medicare population and is associated with high rates of myocardial infarction, stroke, amputation, and death. Nevertheless, national health expenditures for PAD are not known. We hypothesized that PAD-related costs are high, increase with age, and that treatment rates would be less than known PAD prevalence. The objective wa...

increase haemoglobin synthesis and erythro-poiesis. Further clinical and fundamental research is warranted to establish the possible beneficial effects of (oral) iron chelation treatment on RA activity and the anaemia of chronic disease. of hydroxyl radicals in the presence of ferritin and hemosiderin. Is hemosiderin formation a biological protective mechanism? Biochem J 1986; 234: 727-31. Iron...

A 7.1-kbp DNA fragment isolated from a wild strain of Klebsiella oxytoca was sequenced, leading to the identification of 10 open-reading frames (ORFs), including a 504-bp Pad gene. The Pad gene of the Gram-negative bacterium was subsequently expressed in Escherichia coli as a chimeric Pad. The deduced amino acid (AA) sequence of the Pad gene from wild-type K. oxytoca showed approximately 50% ho...

OBJECTIVE Low levels of fetuin-A, a systemic calcification inhibitor, are linked to mortality in patients on dialysis. In contrast, elevated fetuin-A is associated with cardiovascular events in non-renal patients. We investigated fetuin-A in patients with type 2 diabetes and peripheral arterial disease (PAD). RESEARCH DESIGN AND METHODS We studied fetuin-A in 76 patients with PAD and normal g...