نتایج جستجو برای: killing kinetics

تعداد نتایج: 121632  

2018
Yiding Yang Vitaly V. Ganusov

Cytotoxic T lymphocytes (CTLs) have been suggested to play an important role in controlling human immunodeficiency virus (HIV-1 or simply HIV) infection. HIV, due to its high mutation rate, can evade recognition of T cell responses by generating escape variants that cannot be recognized by HIV-specific CTLs. Although HIV escape from CTL responses has been well documented, factors contributing t...

Journal: :international journal of environmental research 2015
a. agah f. doulati ardejani

this paper investigates the importance of considering biomass growth and decay for predicting a field scale microbial degradation of btex plume in an unconfined aquifer system in the pump station area of tehran oil refinery (tor), iran. a two-dimensional finite volume model has been presented to predict multi-species reactive transport incorporating physical, chemical and biological processes i...

2003
Raffaele Rani Alan Barnes

Koutras has proposed some methods to construct reducible proper conformal Killing tensors and Killing tensors (which are, in general, irreducible) when a pair of orthogonal conformal Killing vectors exist in a given space. We give the completely general result demonstrating that this severe restriction of orthogonality is unnecessary. In addition we correct and extend some results concerning Ki...

1996
Xuejia Lai Rainer A. Rueppel

The HKM / HFX cryptosystem is proposed for standardization at the ITU Telecommunication Standardization Sector Study Group 8. It is designed to provide authenticity and colffidentiality of FAX messages at a commercial level of security. In addition, the HKM / HFX cryptosystem is designed for unrestricted export. This paper contains the results of an analysis of the HKM/HFX cryptosystem. Eleven ...

Journal: :Journal of medical primatology 2008
Erik Rollman Rosemarie D Mason Jie Lin Andrew G Brooks Stephen J Kent

BACKGROUND Live attenuated SIV vaccines are highly efficacious, but how they mediate protection is poorly understood. A feature of the effectiveness of live attenuated vaccines is their ability to control high dose challenge viruses early, without a large peak of acute viraemia. We hypothesized that long-lived antigen exposure from live attenuated SIV may result in CD8+ cytotoxic T lymphocytes ...

Journal: :Cancer research 1977
S I Schlager S H Ohanian T Borsos

Line 1, a chemically induced guinea pig hepatoma, is susceptible to killing by anti-Forssman immunoglobulin M antibody and guinea pig complement. When these tumor cells are pretreated with insulin, L-epinephrine, hydrocortisone, or prednisolone, the cells show a marked reduction in their susceptibility to antibody-complement-mediated killing within 15 to 60 min; this effect reverses within 4 hr...

Journal: :Antimicrobial agents and chemotherapy 2006
Emilia Cantón Javier Pemán Macrina Sastre Mónica Romero Ana Espinel-Ingroff

Amphotericin B (AMB), micafungin, and caspofungin MICs, minimal fungicidal concentrations, and time-killing curves were determined in the presence and absence of 10% inactivated serum. AMB was the only agent with consistent killing activity (time required to achieve 99.9% of growth reduction was 2.1 to 3.2 h). The presence of serum enhanced caspofungin activity but lowered those of micafungin a...

Journal: :Journal of immunology 2007
Erik Rollman Miranda Z Smith Andrew G Brooks Damian F J Purcell Bartek Zuber Ian A Ramshaw Stephen J Kent

Both the magnitude and function of vaccine-induced HIV-specific CD8+ CTLs are likely to be important in the outcome of infection. We hypothesized that rapid cytolysis by CTLs may facilitate control of viral challenge. Release kinetics of the cytolytic effector molecules granzyme B and perforin, as well as the expression of the degranulation marker CD107a and IFN-gamma were simultaneously studie...

Journal: :Blood 1973
M J Murphy B I Lord

This paper, the first of a series on the regulation of the hematopoIetic stem cell, examines the effects of stem cell kinetics during an acute exposure to hypoxichypoxia. This physiologic perturbation was chosen because of the well-established role It plays In Influencing erythropoiesis. BDF, male mice were exposed to a simulated altitude of 22,000 ft for periods of time ranging from 3 to 48 hr...

2005
Martin J. Murphy Brian I. Lord

This paper, the first of a series on the regulation of the hematopoIetic stem cell, examines the effects of stem cell kinetics during an acute exposure to hypoxichypoxia. This physiologic perturbation was chosen because of the well-established role It plays In Influencing erythropoiesis. BDF, male mice were exposed to a simulated altitude of 22,000 ft for periods of time ranging from 3 to 48 hr...

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