Small GTPases function as molecular switches in cell signaling, alternating between an inactive, GDP-bound state, and active GTP-bound state. βPix is one of guanine nucleotide exchange factors (GEFs) that catalyze the exchange of bound GDP for ambient GTP. The central goal of this review article is to summarize recent findings on βPix and the role it plays in kidney pathology and physiology. Re...

In this position article, DESCARTES (Developing Education Science and Care for Renal Transplantation in European States) board members describe the current strategies aimed at expanding living and deceased donor kidney pools. The article focuses on the recent progress in desensitization and kidney paired exchange programmes and on the expanded criteria for the use of donor kidneys and organs fr...

this study seek to examine performance of feltham - ohlsen (1995)valuation model at the tehran stock exchange and is trying to identify relation between intrinsic company value and return. this model is trying to determine the intrinsic value of company using their book value. statistical community of this study includes all tse accepted companies and statistical sample is including 37 tse acce...

abstract main objective of this paper is to investigate the impact of exchange rate misalignment on wheat’s producer estimates (pse), using the 1989-2007 period’s data. for this purpose, vector error correction model (vecm) along with the use of real exchange rate based on purchasing power party (ppp) was applied to estimate nominal equilibrium exchange rates. then, by using market price suppor...

The complex multi-criteria optimisation problems arising in Kidney Exchange Programmes have received considerable attention both practice and the scientific literature. Whereas theoretical advancements are well reviewed synthesised, this is not case for practice. We present a synthesis of models methods applied European Programmes, which based on detailed descriptions we created purpose. Most a...

Kidney Exchange Programs (KEP) are valuable tools to increase the options of living donor kidney transplantation for patients with end-stage disease an immunologically incompatible live donor. Maximising benefits a KEP requires information system manage data and optimise transplants. The input specifications systems that relate key on blood group Human Leukocyte Antigen (HLA) types HLA antibodi...