Airway management in critically ill patients remains a fundamental but challenging procedure, characterized by a high rate of complications. Studies have shown that as many as 40% of intubations in critical care settings are accompanied by severe adverse events,1,2 the most frequent complication being hypoxemia. A prospective study from critical care units in Scotland reported that severe hypox...

During bronchoscopy hypoxemia is commonly found and oxygen supply can be delivered by interfaces fed with high gas flows. Recently, the high-flow nasal cannula (HFNC) has been introduced for oxygen therapy in adults, but they have not been used so far during bronchoscopy in adults. Forty-five patients were randomly assigned to 3 groups receiving oxygen: 40 L/min through a Venturi mask (V40, N =...

Background: Hypoxaemia in post-surgical patients of esophageal cancer (EC) is common thoracic departments. However, few studies have investigated the role high-flow nasal cannula (HFNC) compared with conventional oxygen therapy (COT).

OBJECTIVE To systematically analyze the role of heated humidified carbon dioxide (CO2) in laparoscopy. METHODS Clinical trials on laparoscopic procedures using standard dry CO2 versus heated humidified CO2 for pneumoperitoneum were analyzed. RESULTS Ten randomized controlled trials on 565 patients were analyzed. In both the fixed and random effect models, postoperative pain was significantl...

UNLABELLED Patients with COPD using long-term oxygen therapy (LTOT) over 15 h per day have improved outcomes. As inhalation of dry cold gas is detrimental to mucociliary clearance, humidified nasal high flow (NHF) oxygen may reduce frequency of exacerbations, while improving lung function and quality of life in this cohort. In this randomised crossover study, we assessed short-term physiologica...

Despite the absence of clinical safety data, heated, humidified high-flow nasal cannula (HHFNC) therapy is increasingly being used as an alternative to positive-pressure ventilation in pediatrics. This use of HHFNC is “off label” because the US Food and Drug Administration’s approval for these devices was only for air humidification and not as a modality to provide positive distending pressure....