SUMMARY Diagnostic residual and partial residual plots are proposed to identify nonlinearity in covariates for generalized linear models. It is shown that these plots are complement each other in the detection of nonlinearity. In addition, a transformed additive model which allows the resulting residual and partial residual plots to be obtained through the standard least squares approach is pro...

There is emerging epidemiological data to suggest that upper respiratory tract bacterial colonisation in infancy may increase the risk of developing respiratory dysfunction later in life, and respiratory viruses are known to precipitate persistent colonisation. This study utilized a neonatal mouse model of Streptococcus pneumonia (SP) and influenza A virus (IAV) co-infection, where bronchoalveo...

â  a geographical dimension in the poetry of de’bil al- khozaee â  â  abdul rasoul ghaffari * â  â abstractâ in this article, we attempt to study de'bil al-khozaee's poetry. we find him a person who travelled a lot around the west and the east of islamic world. in his journey, he acquired knowledge, belles-letters, morals and also wealth. what is important for us in this research is...

Mycoplasma pneumoniae produces an ADP-ribosylating and vacuolating toxin known as the CARDS (Community Acquired Respiratory Distress Syndrome) toxin that has been shown to be cytotoxic to mammalian cells in tissue and organ culture. In this study we tested the ability of recombinant CARDS (rCARDS) toxin to elicit changes within the pulmonary compartment in both mice and baboons. Animals respond...

BACKGROUND & OBJECTIVES The biochemical mechanisms underlying the development of sensitization-induced airway hyperresponsiveness (AHR) in asthma are poorly defined. Alterations in the regulation of intracellular calcium may play an important role in its pathogenesis. We carried out this study to see the effect of sensitization with ovalbumin on membrane ion fluxes and intracellular calcium in ...

Phosphodiesterase (PDE) inhibitors have potential as alternatives or adjuncts to glucocorticoid therapy in asthma. We compared roflumilast (a selective PDE4 inhibitor) with pentoxifylline (a nonselective inhibitor) and dexamethasone in ameliorating the lesions of chronic asthma in a mouse model. BALB/c mice sensitized to ovalbumin were chronically challenged with aerosolized antigen for 6 weeks...

Tracheal injuries, following blunt neck trauma, are life-threatening surgical emergencies with high risk of mortality. A index suspicion is necessary to avoid missing an occult injury because delays in diagnosis and definitive treatment associated poorer outcomes. We, herein, report a case 28-year man who presented Emergency Department 15 days after trauma from accident involving electric cable...

abstractibn-nubatah is one of the poets of deterioration era who lived at this time so hispoetry has the trace of both the imitation and repetition of the poets of that time. heused a kind of poetic theme in his poems that lacks the privilege and typicality of agood poem because he imitated some poets like emre'al- qays, tarafah ibn al-a’bd,khansa, hassan ibn sabet al-ansary, ka’b ibn ...