Soluble epoxide hydrolase (sEH), a key enzyme in the metabolism of vasodilatory epoxyeicosatrienoic acids (EETs), is sexually dimorphic, suppressed by estrogen, and contributes to underlying sex differences in cerebral blood flow and injury after cerebral ischemia. We tested the hypothesis that sEH inhibition or gene deletion in reproductively senescent (RS) female mice would increase cerebral ...

in order to study on the effect of incomplete sire's pedigree on the prediction of breeding value and estimation of genetic trend, two quantitative traits such as weaning weight and average daily gain with heritabilities 0.15 and 0.30 were simulated. phenotypic, genetic and environmental correlations were assumed 0.5. resulted data files with different proportion of missed sire pedigree (0...

CONTEXT The reproductive endocrinology in Asians and Caucasians is of great interest in view of large differences in prostate cancer rate and sensitivity to pharmacological male contraception. In addition, interpretation of certain antidoping tests is confounded by interethnic variation in androgen disposition. Uridine diphosphoglucuronosyl transferases have a key role in the homeostasis and me...

Streaming is a model where an input graph provided one edge at time, instead of being able to inspect it will. In this work, we take parameterized approach by assuming vertex cover the given, building on work Bishnu et al. [COCOON 2020]. We show further potency combining parameter with Adjacency List streaming obtain results for deletion problems. This includes kernels, algorithms, and lower bo...

Abstract Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system. MS three times more common in women, yet severe men. The mechanisms underlying these sex differences remain largely unknown. initiated by autoreactive T cells, but CNS-infiltrating myeloid cells are key effector driving pathology. role CNS-resident microglial less clear. We have previously sho...

Abstract Background Thalassemia is common in the Iranian population, and it must be considered in the differential diagnosis of the microcytic hypochromic anemia. The molecular analysis of β-thalassemia is necessary for prenatal molecular diagnosis. Α-thalassemia caused by loss of function of either one of the two duplicated α-globin genes or in less frequent non deletion mutations mostly loc...

Security of networks depends on reliable key management systems which generate and distribute symmetrical/asymmetrical encryption/decryption keys between communicating parties. Traditionally, in wired networks, a central server is responsible to generate and distribute the keys securely. But because of no central server or fixed infrastructure exists in mobile ad hoc networks, there are many di...

Reduced genome strain for threonine production http://www.microbialcellfactories.com/content/8/1/2 This paper deals with a key concept in genome engineering; specifically, genome reduction to remove unneeded functions and to enhance desirable cell phenotypes for biotechnology. Genomic engineering Lactococcus lactis http://www.nisr.or.jp/englishHP/report2007/ NISR07hashimoto.pdf Genome deletion ...

PepCs isolated from lactic acid bacteria and bleomycin hydrolases of eukaryotic organisms are strict aminopeptidases which belong to the papain family of thiol peptidases. The structural basis of the enzymic specificity of the lactococcal PepC has been investigated by site-directed mutagenesis. The deletion of the C-terminal residue (Ala-435) abolished the aminopeptidase activity, whereas this ...