The possibility of using glycol chitosan to obtain stabilized liposome containers for doxorubicin delivery is demonstrated. The dissociation constants of the liposome complexes with glycol chitosan (3.4 × 10–4 and 1.10 × 10–5 depending on the aggregation state of the liposomes) are determined. It is shown that the formation of liposome complexes with glycol chitosan has a significant prolongati...

The field of polyelectrolye–protein complexes is now benefiting from the convergence of three themes whose disciplinary distinctions formerly produced fragmentation. Theory and simulations, previously restricted to isotropic models of colloids and polyelectrolytes, are now taking into account the heterogeneity of charges in both macroions and providing far more realistic depictions of proteins....

A novel technique to introduce free amino groups onto polyester scaffolds via aminolyzing the ester groups with diamine has been developed recently. Positively charged chitosan was then deposited onto the aminolyzed poly(l-lactic acid) (PLLA) membrane surface in a layer-by-layer assembly manner using poly(styrene sulfonate, sodium salt) (PSS) as a negatively charged polyelectrolyte. The layer-b...

There are several natural polymers such as carrageenan, alginate, chitin or chitosan that are classified as polysaccharides. One of the most promising is chitosan, deacetylated derivative of chitin, produced from shellfish wastes or fungi [15]. Irradiation of this polymer led the reduction of molecular weight by scission of glycosidic linkage. As compared to the conventional techniques, like ac...

Abstract The quantity and quality of carrageenan produced is influenced by the method extraction solvent. Characterization products necessary to get certain standards so product acceptable consumers both locally internationally. purpose this research was determine solvents that can produce from Kappaphycus alvarezii with best characteristics compare results international in order obtain a stand...

A multiparticulate system of chitosan hydrogel beads has been investigated for colon-specific delivery of macromolecules using fluorescein isothiocyanate-labeled bovine serum albumin as a model protein. The hydrogel bead was formed by polyelectrolyte complexation of chitosan with its counterion, tripolyphosphate (TPP). The protein release experiments were carried out in vitro under different co...