Abstract. We rigorously prove results on spiky patterns for the Gierer-Meinhardt system [8] with a jump discontinuity in the diffusion coefficient of the inhibitor. Using numerical computations in combination with a Turing-type instability analysis, this system has been investigated by Benson, Maini and Sherratt [1], [3], [11]. Firstly, we show the existence of an interior spike located away fr...