BACKGROUND Bisphosphonates, inhibitors of osteoclasts, have been shown to alleviate many of the devastating consequences associated with metastatic bone disease. However, recent reports have shown that bisphosphonates may cause osteonecrosis of the jaws. Since the publication of these initial reports, the authors have treated several patients with osteonecrosis of the jaws who had a history of ...

The newt limb requires nerves for successful regeneration, but the jaw appears to be nerve independent. Among the current hypotheses for the regeneration-inhibitory action of X-rays is one proposing inactivation of nerves as the main cause. We decided to test this hypothesis by comparing the irradiation levels necessary for inhibition of limb and jaw regeneration. Jaws and left front limbs were...

A MODIFICATION of Gillies's plastic needle holder for ophthalmic use was described by the author 17 years ago (Foster, 1938). This consisted in a reduction in size of the handle and scissors-shank of Gillies's instrument, and the replacement of the curved jaws intended to hold needles for intradermal suturing by the jaws of a Quarry Silcock needle holder of average size. The instrument had all ...

OBJECTIVES The aim of this study was to evaluate two commonly used advanced bipolar devices (ENSEAL(®) G2 Tissue Sealers and LigaSure™ Blunt Tip) for compression uniformity, vessel sealing strength, and consistency in bench-top analyses. METHODS Compression analysis was performed with a foam pad/sensor apparatus inserted between closed jaws of the instruments. Average pressures (psi) were rec...

High-performance Web servers are essential to meet the growing demands of the Internet and large-scale intranets. Satisfying these demands requires a thorough understanding of key factors affecting Web server performance. This paper presents empirical analysis illustrating how dynamic and static adaptivity can enhance Web server performance. Two research contributions support this conclusion. F...

The present study shows that an application of cyclophosphamide (CY) supported by dendritic cell (DC)-based vaccines affected differentiation of the activity of CD4+ T cell subpopulations accompanied by an alteration in CD8+ cell number. Vaccines were composed of bone marrow-derived DCs activated with tumor cell lysate (BM-DC/TAgTNF-α) and/or genetically modified DCs of JAWS II line (JAWS II/Ne...

The newt limb requires nerves for successful regeneration, but the jaw appears to be nerve independent. Among the current hypotheses for the regeneration-inhibitory action of X-rays is one proposing inactivation of nerves as the main cause. We decided to test this hypothesis by comparing the irradiation levels necessary for inhibition of limb and jaw regeneration. Jaws and left front limbs were...

THE existence of a giant-cell tumour in the jawbones has been a matter of discussion for many years. In an excellent review Jaffe, Lichtenstein and Portis (1940) tried to clarify some of the problems by denning true giant-cell tumours of bone and separating them from reparative giant-cell granulomas. Later Jaffe (1953) further discussed some of the giant-cell containing lesions of the jaws and ...

The independent evolution of the two toothed jaws of cichlid fishes is thought to have promoted their unparalleled ecological divergence and species richness. However, dental divergence in cichlids could exhibit substantial genetic covariance and this could dictate how traits like tooth numbers evolve in different African Lakes and on their two jaws. To test this hypothesis, we used a hybrid ma...

Rest assured, you're not alone ? people of all ages experience stress at some point during their lives. Since people have different stressors and experience stress differently, it?s difficult to pinpoint or rank the number one cause. But, it might actually surprise you that stress can be beneficial ? and in some cases critical ? in helping individuals respond and adapt to new situations in life...