BACKGROUND Dehydration associated with gastroenteritis is a serious complication. Oral rehydration is an effective and inexpensive treatment, but some physicians prefer intravenous methods. OBJECTIVES To compare oral with intravenous therapy for treating dehydration due to acute gastroenteritis in children. SEARCH STRATEGY We searched the Cochrane Infectious Diseases Group Specialized Regis...

IMPORTANCE Studies comparing the efficacy of intra-arterial therapy (IAT) and medical therapy in reducing final infarct volume (FIV) in intracranial large-vessel occlusions (ILVOs) are lacking. OBJECTIVES To assess whether patients with ILVOs who received IAT have smaller FIVs than patients who received either intravenous tissue plasminogen activator therapy (IVT) or no reperfusion therapy (N...

The GeneChip 3’ IVT Express Kit is the newest option for generating target for Affymetrix 3’ expression arrays. The 3’ IVT Express Kit utilizes the same basic chemistry as GeneChip One-Cycle Target Labeling and Control Reagents, but employs a simplified workflow and optimized reagents that enable lower RNA input and increased ease of use. In this white paper, we describe the technical performan...

BACKGROUND To assess the efficacy of the intravitreal (IVT) injection of Triamcinolone Acetonide (TA) as compared to posterior subtenon (SBT) capsule injection for the treatment of cystoid diabetic macular edema. METHODS Fourteen patients with type II diabetes mellitus and on insulin treatment, presenting diffuse cystoid macular edema were recruited. Before TA injection all focal lakes were t...

purpose : the aim of this study was to evaluate the effect of adjuvant treatments on contrast sensitivity in patients with clinically significant macular edema (csme) treated with macular photocoagulation (mpc). methods : forty eight eyes from 30 patients with non-proliferative diabetic retinopathy (npdr) and csme were included in a prospective randomized clinical trial between august 2008 and ...

Introduction Combined intravenous therapy (IVT) and mechanical thrombectomy (MT) is the standard treatment for acute ischemic stroke (AIS) with large vessel occlusion (LVO). However, use of IVT before MT recently being questioned. Objectives To compare patients treated those alone, in a real-world scenario. Methods Retrospective analysis AIS LVO anterior circulation who underwent MT, or without...

BACKGROUND Despite treatment recommendations from various organizations, oral rehydration therapy (ORT) continues to be underused, particularly by physicians in high-income countries. We conducted a systematic review of randomised controlled trials (RCTs) to compare ORT and intravenous therapy (IVT) for the treatment of dehydration secondary to acute gastroenteritis in children. METHODS RCTs ...

OBJECTIVE To compare the efficacy of an intravitreal injection to a posterior subtenon injection of triamcinolone acetonide for the treatment of diffuse diabetic macular edema. MATERIALS AND METHODS Sixty patients with diabetes mellitus presenting with diffuse diabetic macular edema were recruited for the study. In each patient, one eye received a 4.0 mg (0.1 mL) intravitreal (IVT) injection ...

BACKGROUND The clinical benefit of intravenous thrombolysis (IVT) in acute ischemic stroke is time dependent. Several studies report a short median door-to-needle time (DNT; 20 min), mainly in large tertiary referral hospitals equipped with a level 1 emergency department, a dedicated stroke team available 24/7, and on-site neuroimaging facilities. Meanwhile, in daily practice, the majority of s...