For validating low level embedded software, engineers use simulators that take the real binary as input. Like the real hardware, these full-system simulators are organized as a set of components. The main component is the CPU simulator (ISS), because it is the usual bottleneck for the simulation speed, and its development is a long and repetitive task. Previous work showed that an ISS can be ge...

Parkinson's disease (PD) is characterized by pathological changes within several deep structures of the brain, including the substantia nigra and caudate nucleus. However, changes in interstitial fluid (ISF) flow and the microstructure of the interstitial space (ISS) in the caudate nucleus in PD have not been reported. In this study, we used tracer-based magnetic resonance imaging (MRI) to quan...

OBJECTIVE Idiopathic short stature (ISS) is a heterogeneous disorder. An impairment of growth hormone (GH)/insulin-like growth factor 1 (IGF-1)/IGF-1 receptor (IGF-1 R) axis is postulated. To evaluate the somatotropic axis in relation to body mass index (BMI), serum IGF-1, IGF-binding protein-3 (IGFBP-3) and the expression of IGF-1 R genes in patients with ISS. METHODS Fifty-five ISS patients...

We have developed an Informative Sample Subspace (ISS) method that is suitable for projecting high dimensional data onto a low dimensional subspace for classification purposes. In this paper, we present an ISS algorithm that uses a maximal mutual information criterion to search a labelled training dataset directly for the subspace’s projection base vectors. We evaluate the usefulness of the ISS...

The evaluation of information systems (ISs), especially in the healthcare field, is a complex task. Evidently, there is a need for better understanding of the different aspects evaluation. While in the general IS science field there have been several attempts to build frameworks and models to better understand the evaluation of ISs, in healthcare similar frameworks have been almost nonexistent....

We consider the problem of achieving disturbance attenuation in the ISS and integral-ISS sense for nonlinear systems using bounded controls. For the ISS case we derive a universal formula which extends an earlier result of Lin and Sontag to systems with disturbances. For the integral-ISS case we give two constructions, one resulting in a smooth control law and the other in a switching control l...

BACKGROUND The International Space Station (ISS) is a unique built environment due to the effects of microgravity, space radiation, elevated carbon dioxide levels, and especially continuous human habitation. Understanding the composition of the ISS microbial community will facilitate further development of safety and maintenance practices. The primary goal of this study was to characterize the ...

Organizations need to protect information assets against cyber crime, denial-of-service attacks, web hackers, data breaches, identity and credit card theft, and fraud. Criminals often try to achieve financial, political, or personal gain through these attacks, so the threats that their actions prompt are insidious motivators for organizations to adopt information systems security (ISS) approach...

OBJECTIVE To evaluate outcomes of radical excision of feline injection-site sarcomas (ISS) via assessment of local recurrence and metastasis rates, survival times, and complications associated with surgery. DESIGN Retrospective case series. ANIMALS 91 cats with ISS. PROCEDURES Medical records of cats that had radical excision of ISS without adjunctive treatment were reviewed. Information ...

From a theoretical investigation of the continuity of wastewater organic (COD) and N compounds along the links connecting the primary settling tank (PST), fully aerobic or N removal activated sludge (AS) treating raw and settled wastewater and aerobic digestion unit operations, it was found that the PS characteristics, viz. the biodegradable and unbiodegradable soluble and particulate COD and N...