Numerical simulations for free surface flow models, which are water entry of several rigid bodies, fluid tank sloshing and flood disaster over several rigid bodies were conducted by using an Incompressible smoothed particle hydrodynamics (ISPH) method. The governing equations are discretized and solved with respect to Lagrangian moving particles filled within the mesh-free computational domain ...

Mycobacterium tuberculosis synthesises isoprenoid precursors via the MEP/DOXP pathway and at least five enzymes in the pathway (Dxs1, Dxr/IspC, IspD, IspF, and GcpE/IspG) are required for growth in vitro. We investigated the role of LytB (IspH) in M. tuberculosis; M. tuberculosis is unusual in that it has two homologs-LytB1 and LytB2. We were unable to delete the lytB2 gene unless we provided a...

Liquid sloshing is a common phenomenon in the transporting of liquid tanks. Liquid waves lead to fluctuating forces on the tank wall. If these fluctuations are not predicted or controlled, they can lead to large forces and momentum. Baffles can control liquid sloshing fluctuations. One numerical method, widely used to model the liquid sloshing phenomena is Smoothed Particle Hydrodynamics (SPH)....

This study presents numerical simulations on double-diffusive flow of a nanofluid in two cavities connected with four vertical gates. Novel shape an outer square mounted cavity by gates was used. Heterogeneous porous media and Al 2 O 3 -water are filled...

The isoprenoid biosynthesis pathways produce the largest class of small molecules in Nature: isoprenoids (also called terpenoids). Not surprisingly then, isoprenoid biosynthesis is a target for drug discovery, and many drugs--such as Lipitor (used to lower cholesterol), Fosamax (used to treat osteoporosis), and many anti-infectives--target isoprenoid biosynthesis. However, drug resistance in ma...

Fluid mixing is a crucial and challenging process for microfluidic systems, which are widely used in biochemical processes. Because of their fast performance, active micromixers that use stirrer blades are considered for biological applications. In the present study, by using a robust and convenient Incompressible Smoothed Particle Hydrodynamics (ISPH) method, miscible mix...