BACKGROUND Inclusion of inhomogeneity corrections in intensity modulated small fields always makes conformal irradiation of lung tumor very complicated in accurate dose delivery. OBJECTIVE In the present study, the performance of five algorithms via Monte Carlo, Pencil Beam, Convolution, Fast Superposition and Superposition were evaluated in lung cancer Intensity Modulated Radiotherapy planni...

BACKGROUND We report the use of salvage radiosurgery to manage an aggressive olfactory neuroblastoma (esthesioneuroblastoma) with multiple recurrences and intracranial extension. CASE PRESENTATION A 43-year-old Caucasian woman presented 11 years ago with progressive nasal blockage and headaches. A necrotic polyp originating in her left middle meatus and extending to the ethmoid air cells and ...

BACKGROUND We assessed the robustness of passive scattering proton therapy (PSPT) plans for patients in a phase II trial of PSPT for stage III non-small cell lung cancer (NSCLC) by using the worst-case scenario method, and compared the worst-case dose distributions with the appearance of locally recurrent lesions. METHODS Worst-case dose distributions were generated for each of 9 patients who...

BACKGROUND The aim of this study was to assess if FDG-PET could guide dose prescription heterogeneity and decrease arbitrary location of hotspots in SBRT. METHODS For three patients with stage I lung cancer, a CT-simulation and a FDG-PET were registered to define respectively the PTVCT and the biological target volume (BTV). Two plans involving volumetric modulated arc therapy (VMAT) and simu...

Introduction Polymer gel dosimeters offer a practical solution to 3D dose verification for conventional radiotherapy as well as intensity-modulated and stereotactic radiotherapy. In this study, EGSnrc calculated and PAGAT polymer gel dosimeter measured dose profiles from single shot irradiation with 18 mm collimator of Gamma Knife in homogeneous and inhomogeneous phantoms were compared with eac...

Aim: To compare the high dose rate (HDR) brachytherapy treatment planning using standard orthogonal radiography and computerized tomography (CT) for carcinoma of the cervix. Methods: Forty applications with orthogonal planning using the Brachy Vision treatment planning system version 7.3.10 were performed. Orthogonal and CT based planning in these applications were compared; the doses to point ...

The Leksell Gamma Knife [Elekta Corp] uses helmets as collimators to produce four standard beam sizes. The nominal beam diameters are 18, 14, 8, and 4 mm. During computer treatment planning for gamma knife stereotactic radiosurgery, the size of the treated volume may differ from the standard beam sizes. To maintain conformality of the isodose curves to the treated volume, beam sizes may be supe...

The importance of medical physics methods in modern radiation therapy is shown. types irradiation used are considered. At each stage, it necessary to maintain high accuracy all procedures. One the significant stages treatment planning, where quality control plan carried out ensure patient. process plans with intensity modulation (Volumetric Modulated Arc Therapy - VMAT) on VitalBeam linear acce...

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background: in radiation therapy, the sparing of normal tissues can be performed using either multi-leaf collimators or cerrobend blocks. the current work focuses on the physical characteristics of cerrobend blocks including attenuation coefficient, effective penumbra width and isodose curves undulation in penumbral regions. materials and methods: all measurements were performed using a dual en...