Studies were conducted on the physical properties of Enzyme I, the first protein in the Salmonella typhimurium phosphoenolpyruvate:glycose phosphotransferase system. Since values lower than those previously reported for the monomer molecular weight were obtained, experiments were performed to determine whether Enzyme I had been partially degraded during isolation of homogeneous protein. Crude e...

We have performed high level ab initio quantum mechanical calculations for aminoethene and the three isomeric 1,1- (Z)- or (E)-1,2-diaminoethenes as well as their singly and doubly charged cations derived by loss of electrons and/or upon protonation. Gas phase molecular structures were computed at the MP2/6-311+G(3df,2p) level. Standard molar enthalpies of formation in the gas phase, at T = 298...

The presence of a bulky peripheral wedge destabilizes the homo-assembly of an amide functionalized acceptor (A) monomer and thereby enables the formation of an alternating supramolecular copolymer with an amide appended donor (D) monomer via the synergistic effect of H-bonding and the charge-transfer (CT) interaction with a remarkably high Ka of 31 000 M-1. In sharp contrast, H-bonding driven h...

ni6(n2h4)6(so4)4(oh)2(h2o)8](so4)(h2o)10 complex was prepared according to literature report. the reaction between aforementioned complex via sodium alkoxides as a reactants, were carried out in the solid state. the [ni6(n2h4)6(so4)4(oh)2(h2o)8](so4)(h2o)10 undergoes an intramolecular two electrons oxidation-reduction reaction at room temperature and metallic nickel nanoparticles (ni1-ni5) was ...

ni6(n2h4)6(so4)4(oh)2(h2o)8](so4)(h2o)10 complex was prepared according to literature report. the reaction between aforementioned complex via sodium alkoxides as a reactants, were carried out in the solid state. the [ni6(n2h4)6(so4)4(oh)2(h2o)8](so4)(h2o)10 undergoes an intramolecular two electrons oxidation-reduction reaction at room temperature and metallic nickel nanoparticles (ni1-ni5) was ...

background : following establishment of iranian adverse drug reaction (adr) monitoring  center  in  1997, adr  committees  were  established  in  all  hospitals  of mazandaran province of iran. clinical pharmacists from mazandaran university of medical sciences have been involved with these committees since 2007. the aim of this study was to compare the results of the pharmacovigilance system b...

The complete conformational space of monomeric 1,3-butanediol has been characterized theoretically, and 73 unique stable conformers were found at the MP2/6-311++G(d,p) level. These were classified into nine families whose members share the same heavy atom backbone configurations and differ in the hydrogen atom orientations. The first and third most populated backbone families are governed by th...

The aggregation of insulin is complicated by the coexistence of various multimers, especially in the presence of Zn(2+). Most investigations of insulin multimerization tend to overlook aggregation kinetics, while studies of insulin aggregation generally pay little attention to multimerization. A clear understanding of the starting multimer state of insulin is necessary for the elucidation of it...

Proton-bound dimers consisting of two glycerophospholipids with different headgroups were prepared using negative ion electrospray ionization and dissociated in a triple quadrupole mass spectrometer. Analysis of the tandem mass spectra of the dimers using the kinetic method provides, for the first time, an order of acidity for the phospholipid classes in the gas phase of PE < PA << PG < PS < PI...

The self-association of small aromatic systems driven by π-π stacking and hydrophobic interactions is well-known. Understanding the nature of these interactions is important if they are to be used to control association. Here, we present results of an NMR study into the self-association of two isomers of naphthoic acid along with an investigation into the role of a fluorine substituent on that ...