نتایج جستجو برای: ischemiareperfusion leukocyte infiltration

تعداد نتایج: 83735  

Journal: :International immunology 2000
S C Tromp M G oude Egbrink R P Dings S van Velzen D W Slaaf H F Hillen G J Tangelder R S Reneman A W Griffioen

Leukocyte-endothelium interactions are diminished in tumors. It is reported here that, in a tumor-free in vivo model, angiogenic factors can down-regulate leukocyte adhesion to endothelium. Slow releasing pellets were loaded with either basic fibroblast growth factor (bFGF), vascular endothelial cell growth factor (VEGF) or vehicle alone and were placed in the scrotum of mice. After 3 days, a s...

Journal: :FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001
E E Eriksson X Xie J Werr P Thoren L Lindbom

Leukocyte infiltration in atherosclerosis has been extensively investigated by using histological techniques on fixed tissues. In this study, intravital microscopic observations of leukocyte recruitment in the aorta of atherosclerotic mice were performed. Interactions between leukocytes and atherosclerotic endothelium were highly transient, thereby limiting the ability for rolling leukocytes to...

2013
Yoke Keong Yong NurShahira Sulaiman Muhammad Nazrul Hakim Gwendoline Ee Cheng Lian Zainul Amirudin Zakaria Fauziah Othman Zuraini Ahmad

The aim of the present study was to evaluate the anti-inflammatory activities of aqueous extract of Bixa orellana (AEBO) leaves and its possible mechanisms in animal models. The anti-inflammatory activity of the extract was evaluated using serotonin-induced rat paw edema, increased peritoneal vascular permeability, and leukocyte infiltrations in an air-pouch model. Nitric oxide (NO), indicated ...

Journal: :Journal of immunology 2002
Cécile Guillot Carole Guillonneau Patrick Mathieu Christian A Gerdes Séverine Ménoret Cécile Braudeau Laurent Tesson Karine Renaudin Maria G Castro Pedro R Löwenstein Ignacio Anegon

Previous work on blockade of CD40-CD40 ligand interaction in mice and primates with anti-CD40 ligand mAbs has resulted in a moderate prolongation of allograft survival without the development of true allograft tolerance. In this study, we show in rats that adenovirus-mediated gene transfer of CD40Ig sequences into the graft resulted in prolonged (>200 days) expression of CD40Ig and in long-term...

2017
Hong Chen Gang Chen Claire Condron

Purpose: Gut permeability and microvascular injury following ischaemia/reperfusion (IR) have been implicated in the systemic inflammatory response syndrome (SIRS) and multiple organ failure (MOF). Taurine (TAU), a sulfurcontaining amino acid, is a powerful antioxidant and regulator of intracellular calcium and several studies have established that treatment with TAU protects cerebral, cardiac a...

Journal: :Journal of neurosurgery 1995
K Roessler G Suchanek H Breitschopf K Kitz C Matula H Lassmann W T Koos

Tumor necrosis factor-alpha (TNF alpha) protein and messenger (m)RNA distribution was studied in biopsy samples of glial brain tumors, using immunohistochemistry and in situ hybridization with molecular probes, to investigate the role of this cytokine in tumor proliferation and immunological host defense. Focal expression of TNF alpha was detected in four of four glioblastomas, one of two anapl...

Journal: :Journal of leukocyte biology 1996
N W Lukacs R M Strieter S W Chensue S L Kunkel

Allergic airway inflammation is characterized by peribronchial eosinophil accumulation with the submucosa surrounding the airway. The initial induction of immunoglobulin E (IgE)-mediated mast cell degranulation, up-regulation of adhesion molecules, and the production of inflammatory and chemotactic cytokines, leading to the infiltration of specific leukocyte subsets, is orchestrated in a sequen...

2007
Jose Miguel Cerda-Nicolas Stephen Poole Peter J Jose Julio Cortijo Esteban J Morcillo Teresa Mateo Yafa Naim Abu Nabah Mercedes Losada Rossana Estelles Chantal Company Rossana Estellés Begoña Bedrina Jose Miguel Cerdá-Nicolás Peter J. Jose Esteban J. Morcillo Maria-Jesus Sanz

Angiotensin II (Ang-II) exerts inflammatory activity and is involved in different cardiovascular disorders. This study has evaluated the involvement of TNFα in the leukocyte accumulation elicited by Ang-II. Ang-II (1 nmol/L, i.p., in rats) induced TNFα release at 1h followed by neutrophil and mononuclear cell recruitment. The administration of an anti-rat TNFα antiserum had no effect on Ang-II-...

2015
Noriko Okuno Sadaya Matano

Primary thyroid T-cell lymphoma is rare, with only 19 cases reported previously. T-cell prolymphocytic leukemia/ lymphoma (T-PLL) is a rare entity among T-cell lymphomas. T-PLL patients present with hepatosplenomegaly, lymphadenopathy, skin infiltration and a high leukocyte count, sometimes with anaemia and thrombocytopenia, but thyroid infiltration has been reported in only one other case. Her...

Journal: :The Journal of dermatology 1999
H I Chi M Arai

A 41-year-old woman developed skin vesicles one week before examination. She had been suffering from ulcerative colitis since the age of 30. Histologic examination of a vesicle showed a subepidermal bulla accompanied by mononuclear leukocyte infiltration intermingled with eosinophils and neutrophils. Eosinophilia was also noted. Direct immunofluorescent test revealed linear deposits of IgA in t...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید