conclusions treatment with epo and mel had a beneficial effect on renal ir injury. the results may also indicate that mel protects against morphological damage better than epo in renal ir injury. results ischemia-reperfusion significantly decreased the observed hb and hct values. the histopathological findings in the ir group confirmed that there was an increase in the hyaline cast and thickeni...

background: stroke is a multifactorial disorder, the most common cause being arterial occlusion. transcranial doppler ultrasonography (tcd) is a common non-invasive method available for assessment the arterial blood flow of the brain. objective: assessment the hemodynamic parameters of cerebral arteries, using tcd device in patients suffering ischemic stroke. materials and methods: this descrip...

introduction: stroke is one of the most important reasons of death. hence, trials to prevent or lessen the complications originated by stroke are a goal of public health worldwide. the ischemia-reperfusion causes hypoxia, hypoglycemia and incomplete repel of metabolic waste products and leads to accumulation of free radicals triggering neuronal death. the a1 adenosine receptoras an endogenous l...

oxygen free radicals may be implicated in the pathogenesis of ischemia reperfusion damage. as the antioxidant effects of some species of pistacia have been reported, the protective effects of pistacia vera l. gum extract (0.1-0.5 g/kg) on oxidative damage following cerebral ischemia were studied in rats. ischemia was induced using four-vessel occlusion model and evaluated using measurement of m...

ischemia reperfusion injury is the tissue damage caused when blood supply returns to the tissue after a period of ischemia or lack of oxygen. ischemia reperfusion induces cell death and endemic reaction that is one of the most important clinical problems with acute renal failure and renal transplantation. in this study, the effect of pentoxifylline on rat kidney function and cell injury followi...

objective(s): cerebral ischemia is often associated with cognitive impairment. oxidative stress has a crucial role in the memory deficit following ischemia/reperfusion injury. α-terpineol is a monoterpenoid with anti-inflammatory and antioxidant effects. this study was carried out to investigate the effect of α-terpineol against memory impairment following cerebral ischemia in rats. materials a...