PURPOSE AND METHODS Migraine, with or without aura, affects from 10% to 14% of the population, and is as such one of the most common headache disorders. A unified hypothesis for the physiopathology of migraine and its relationship with epileptic migraine and migralepsy has yet to be formulated. Trigemino-vascular system (TVS) activation is believed to play a crucial role in the "pain phase" in ...

We are talking about the most beautiful woman in the world, about the largest cave in Europe, about the best sportsman of a particular year. We have even started to rank companies according to their ‘‘intellectual assets’’, universities according to their ‘‘importance’’, and scientists according to their ‘‘impact’’. It is time that we protest against this culture of ‘‘linearity’’ in a world tha...

Cancer Epidemiology Unit, Department of Medical Sciences, University of Turin, Turin, Italy, Centre for Statistical Methodology, London School of Hygiene and Tropical Medicine, London, UK, Departments of Medical Statistics and Non-communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK and Centre for Public Hea...

The transcriptional activity of a human transposon-like family of repeats, called the THE-1 family, has been studied in cell culture and in human tissue. Both strands of THE-1 are present in several discrete length poly A plus RNAs. Primer extension studies and the structures of cDNA clones show that these THE-1 transcripts are usually the product of other transcription units. The THE-1 LTR pro...

machining operation is one of the most applicable processes for the manufacturing of industrial parts. usually, the quality of finished part in turning operation is measured in terms of surface roughness. in turn, surface quality is determined by machining parameters and tool geometry specifications. the main objective of this study is to model and optimize machining parameters and tool geometr...

the systematics, morphology, distribution, biology, economic importance and conservation of the lamprey of iran are described, the species is illustrated, and a bibliography on this fish in iran is provided. there is one native and endemic species in the caspian sea basin, caspiomyzon wagneri . the genus caspiomyzon is characterised by having 2 dorsal fins, an oral disc narrower than the body, ...