نتایج جستجو برای: irreversible electroporation
تعداد نتایج: 28638 فیلتر نتایج به سال:
Electrochemotherapy is an emerging local treatment for the management of superficial tumors and, among these, also chest wall recurrences from breast cancer. Generally, the treatment of this peculiar type of tumor requires the coverage of large skin areas. In these cases, electrochemotherapy treatment by means of standard small size needle electrodes (an array of 0.73 cm spaced needles, which c...
In the cooperation with the European partners, the medical device called CliniporatorTM (IGEA s.r.l., Carpi, Italy) was developed, in the frame of the Cliniporator project (2000-03) funded by European Community. This device was designed for controlled in vivo cell permeabilization by electroporation. Electroporation is used to provide access to molecules distributed freely in the vascular and e...
The electroporation technique utilizes pulsed electric fields to induce porous defects in the cell membrane, and can be used for delivering drugs into cells killing cancer cells. To develop an pulse protocol clinic with this technique, key issue is understand evolution of pores membrane during process electroporation. This paper presents a study address issue. Specifically, mathematical model s...
Many approaches for studying the transmembrane potential (TMP) induced during the treatment of biological cells with pulsed electric fields have been reported. From the simple analytical models to more complex numerical models requiring significant computational resources, a gamut of methods have been used to recapitulate multicellular environments in silico. Cells have been modeled as simple s...
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