During the routine examination of sternal marrow smears it was observed that the presence of nuclear fragments in red cell precursors, commonly known as Howell-Jolly bodies, was usually associated with clear evidence of vitamin B12 or folic acid deficiency. Moreover, this seemed to be so even when the megaloblastic transformation of erythropoiesis was not well developed. With further experience...

BACKGROUND The prevalence of anaemia and iron deficiency in women remains high worldwide. WHO recommends weekly iron-folic acid supplementation where anaemia rates in non-pregnant women of reproductive age are higher than 20%. In 2006, a demonstration project consisting of weekly iron-folic acid supplementation and regular de-worming was set up in two districts in a northern province in Vietnam...

To determine the association of smoking with other health-compromising behavior and beliefs during pregnancy, a cross-sectional survey of 1,203 women in the United Kingdom assessed smoking status, stage of change, fetal health locus of control, alcohol consumption, folic acid intake, and use of vitamin and iron supplements. Twenty percent were current smokers, and 33% were alcohol users. Pregna...

       The anti-apoptotic gene bcl-2 is located in mitochondria, but it is uncertain whether its expression affects hepatocyte survival in ischemia/reperfusion (I/R) injury. This experiment was designed to evaluate the role of folic acid in expression of bcl-2 in I/R in rat liver. Eighteen Wister rats were divided into sham-operated controlgroup (C) (n=6), I/R group (...

The Early Nutrition Academy and the European Commission-funded EURRECA Network of Excellence jointly sponsored a scientific workshop on critical micronutrients in pregnancy, lactation, and infancy. Current knowledge and unresolved questions on the supply of vitamin D, folic acid, and iron for pregnant women, lactating women, and infants, and their health effects were discussed. The question was...

The risk factors for maternal anemia (hemoglobin level less than 110 g/L) were studied in human immunodeficiency virus-negative pregnant women in Benin at the time of first antenatal visit and prior to any prevention. Data for the first 1,005 pregnant women included in a multicentre randomized controlled trial were analyzed. Anemia was common (68.3%), and malaria and helminth infestations were ...

in order to study the effect of folic acid on seed reserves partitioning and early vigor of seedlings of kavir wheat cultivar, an experiment was conducted in a completely randomized design with 0, 12.5, 25, 50, 100 and 200 mm of folic acid. results of this study indicated that dry weight of seeds decreased in a same pattern in all treatments and about 6-8% of total seed was structural section. ...

the anti-apoptotic gene bcl-2 is located in mitochondria, but it is uncertain whether its expression affects hepatocyte survival in ischemia/reperfusion (i/r) injury. this experiment was designed to evaluate the role of folic acid in expression of bcl-2 in i/r in rat liver. eighteen wister rats were divided into sham-operated controlgroup (c) (n=6), i/r group (n=6), folic acid treated group whi...

Such "therapy" effectively consists of recommending a multivitamin-mineral supplement with somewhat higher-than-daily-value amounts of several of the B vitamins (pyridoxine hydrochloride [B6], cyanocobalamin [B12], and folic acid). Therapy with, for example, 25 mg of B6, 100 μg of B12, and 400 μg of folic acid is simply obtained in a high "potency" (no-iron) multivitamin that can be bought in t...