The application of Mössbauer spectroscopy for the determination of the valance states of iron is obvious. However, in case of iron in tissues, this method often fails due to the low concentration of Mössbauer probe. On the other hand, the X-ray Absorption Near Edge Spectroscopy (XANES) requires a smaller amount of iron, but the acquired information on iron oxidation states is not straightforwar...

BACKGROUND This study analysed, in vivo and in vitro, the effects of four different intravenous iron preparations (iron gluconate, iron sucrose, iron dextran and ferric carboxymaltose) on activation and damage of mononuclear cells. METHODS A randomized prospective study was conducted in 10 haemodialysis (HD) patients. Blood samples were collected at baseline (T0); 1 h after starting HD, just ...

a series of ortho -hydroxypyridine-4-ones were prepared in high yields and evaluated for antioxidant and iron chelating activities. n 1 -h hydroxypyridinones va , vb , and ve were the best radical scavengers in dpph free radical scavenging assay. compound vb was proved to be the most potent compound in hydrogen peroxide scavenging assay. all of the synthesized compounds had very close chelating...

The spin state of cytochrome P-450 ferric iron in uiuo and in oitro was examined in freshly prepared liver microsomes from rabbit, guinea pig, hamster, mouse, and rat by low temperature electron paramagnetic resonance CEPR) spectroscopy and compared with room temperature difference spectral changes. Simple liquids of known relatively “pure” type I, reverse type I, and type II tcyclohexane, buta...

Evidence is accumulating that Mycobacterium leprae is probably a microbe­ dependent microbe. l O1 3 The first report that multiplication of M. leprae was promoted by a growth factor of mycobacterial origin was proposed by Twort l 9 in 1 9 1 0 , two years before the discovery of the cultivation of 'lohne's bacilli' in media enriched with heat-killed mycobacteria . 2o The growth factor was identi...

Brain iron accumulation has been associated with inciting the generation of oxidative stress in a host of chronic neurological diseases, including Parkinson's disease. Using the catecholaminergic neurotoxin 6-hydroxydopamine to lesion cellular dopaminergic pathways as a model of Parkinson's disease in culture, a selection of 1-hydroxypyridin-2-one (1,2-HOPO) metal chelators were synthesized and...

We argue that, because of quantum entanglement, the local physics of strongly correlated materials at zero temperature is described in a very good approximation by a simple generalized Gibbs distribution, which depends on a relatively small number of local quantum thermodynamical potentials. We demonstrate that our statement is exact in certain limits and present numerical calculations of the i...

The syntheses of 4-mercapto-2,6-di(pyrazol-1-yl)pyridine (bppSH) and bis[2,6-di(pyrazol-1-yl)pyrid-4-yl]disulfide (bppSSbpp) are reported. In contrast to previously published "back-to-back" bis-[2,6-di(pyrazol-1-yl)pyridine] derivatives, which form coordination polymers with transition ions that are usually insoluble, bppSSbpp yields soluble oligomeric complexes with iron(ii) and zinc(ii). Mass...

An organically templated iron sulfate of the formula @HN(CH2)6NH#@Fe Fe2 F6(SO4)2#•@H3O# possessing the kagomé lattice has been prepared and characterized by single-crystal crystallography and other techniques. This mixed-valent iron compound shows complex magnetic properties including spin-glass behavior and magnetic hysteresis. The low-temperature specific heat data show deviation from the T ...