BACKGROUND Effects of prenatal iron supplementation on maternal postpartum iron status and early infant iron homeostasis remain largely unknown. OBJECTIVE We examined iron absorption and growth in exclusively breastfed infants in relation to fetal iron exposure and iron status during early infancy. DESIGN Longitudinal, paired iron-absorption (⁵⁸Fe) studies were conducted in 59 exclusively b...

background: thalassemia is a series of hemoglobinopathies in which the production of perfect hemoglobin is completely or partially suppressed. using injectable iron chelators have been dominating treatment for the iron overload caused by recurrent blood transfusions in thalassemic patients, however, a new oral iron chelating drug (exjade) have been recently introduced and might be cost effectiv...

hydroxypyridinone iron chelators are currently the main candidates for development of orally active iron chelating alternatives to desferrioxamine (dfo). in the present study, the relative efficacy and liver toxicity of a bidentate chelator, 2-methyl-3-hydroxypyridin-4-one (mhpo), was studied in iron overloaded rats and compared with those of dfo. for iron overloading, rats received i.p. inject...

in order to study the effect of  foliar application of zinc and iron on germination of soybaen seed under different level of irrigation, an experiment was conducted in 2009 at shahrekord agricultural research center. main factor was including of four levels of drought stress as irrigation (irrigation after 60, 80, 100 and 120 mm evaporation from class a evaporation basin) and sub factor was inc...

aims: arsenic contamination of natural water resources has become an important environmental problem in the world. the adsorption method by iron filings adsorbent or zero-valent iron was used. the study aimed to evaluate the efficiency of iron filings in arsenite removal from polluted water and to investigate the effect of magnetic field on the process. materials & methods: this interventional ...

indium is a heavy metal belonging to group iiia. it is believed that indium may interfere with iron metabolism from the sites of absorption, transportation, utilization and storage in the cells. the present investigation was established to study and compare the binding of iron and indium to human apo-transferrin (apo-tf). pure human apo-tf was used and the binding activity of iron and indium, a...

objective: although iron is a crucial element for many metabolic pathways of the body, the excess iron may induce apoptosis in some cell types such as macrophages. in the present investigation, the role of iron overload in inducing apoptosis of balb/c mice macrophages infected with l. major in vitro, as a selective model, was studied. materials and methods: the peritoneal macrophages were harve...

Iron is essential for most living organisms. Plants transcriptionally induce genes involved in iron acquisition under conditions of low iron availability, but the nature of the deficiency signal and its sensors are unknown. Here we report the identification of new iron regulators in rice, designated Oryza sativa Haemerythrin motif-containing Really Interesting New Gene (RING)- and Zinc-finger p...