Electron-beam lithography (EBL) was used to define an aminosilane nanopatterned surface in order to electrostatically self-assemble gold nanoparticles (Au NPs). The chemically modified nanopatterned surfaces were immersed into a Au NP solution to allow the Au NPs to self-assemble. Equilibrium self-assembly was achieved in only 20 min. The number of Au NPs that self-assembled on an aminosilane d...

Synaptic activity-dependent changes in the spatio-temporal distribution of calcium ions regulate important neuronal functions such as dendritic integration and synaptic plasticity, but the processes that terminate the free Ca2+ transients associated with these changes remain unclear. We have characterized at the electron microscopic level the intracellular compartments involved in buffering fre...

The history of electron probe analysis in the USA in its first two decades is reviewed, with reference to the personalities which were involved, the development of instrumentation and theory, and the technical problems and limitations of that era.

This article, dedicated to the memory of the late professor Raimond Castaing, will evoke the birth and the first developments of electron probe microanalysis in France.